V
Volker Vielhauer
Researcher at Ludwig Maximilian University of Munich
Publications - 61
Citations - 4103
Volker Vielhauer is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Chemokine receptor & Chemokine. The author has an hindex of 31, co-authored 60 publications receiving 3716 citations.
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Journal ArticleDOI
Expression and Characterization of the Chemokine Receptors CCR2 and CCR5 in Mice
Matthias Mack,Josef Cihak,Christopher Simonis,Bruno Luckow,Amanda E. I. Proudfoot,Jir̆í Plachý,Hilke Brühl,Michael Frink,Hans-Joachim Anders,Volker Vielhauer,Jochen Pfirstinger,Manfred Stangassinger,Detlef Schlöndorff +12 more
TL;DR: Both Abs appear as useful reagents to further study the role of CCR2 and CCR5 in murine disease models and in good correlation to these in vitro data, MC-21 almost completely prevented the influx of monocytes in thioglycollate-induced peritonitis.
Journal ArticleDOI
Chemokines and chemokine receptors are involved in the resolution or progression of renal disease
TL;DR: The present data on the role of chemokines in acute and chronic renal disease with special emphasis on their potential role in mediating resolution or progression of renal disease as well as on therapeutic options are summarized.
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Chemokine Expression Precedes Inflammatory Cell Infiltration and Chemokine Receptor and Cytokine Expression during the Initiation of Murine Lupus Nephritis
Guillermo Pérez de Lema,Holger Maier,Elena Nieto,Volker Vielhauer,Bruno Luckow,Francisco Mampaso,Detlef Schlöndorff +6 more
TL;DR: The hypothesis that chemokines initiate leukocyte infiltration and precede proteinuria and renal damage in MRL/lpr mice is supported and chemokine generation is restricted to sites of subsequent inflammatory cell infiltration and the onset of proteinuria.
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Activation of toll-like receptor-9 induces progression of renal disease in MRL-Fas(lpr) mice
Hans-Joachim Anders,Volker Vielhauer,Vaclav Eis,Yvonne Linde,Matthias Kretzler,Guillermo Pérez de Lema,Frank Strutz,Stefan Bauer,Mark Rutz,Hermann Wagner,Hermann Josef Gröne,Detlef Schlöndorff +11 more
TL;DR: It is concluded that TLR9 activation triggers disease activity of systemic autoimmunity, for example, lupus nephritis, and that adaptive and innate immune mechanisms contribute to the CpG‐DNA‐induced progression of lupulonephritis.
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A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation.
Hans-Joachim Anders,Volker Vielhauer,Michael Frink,Yvonne Linde,Clemens D. Cohen,Simone Monika Blattner,Matthias Kretzler,Frank Strutz,Matthias Mack,Hermann Josef Gröne,James Onuffer,Richard Horuk,Peter J. Nelson,Detlef Schlöndorff +13 more
TL;DR: It is concluded that CCR1 blockade may represent a new therapeutic strategy for reducing cellular infiltration and renal fibrosis as major factors in the progression to end-stage renal failure.