W
W. M. G. Tunbridge
Researcher at Royal Victoria Infirmary
Publications - 8
Citations - 1046
W. M. G. Tunbridge is an academic researcher from Royal Victoria Infirmary. The author has contributed to research in topics: Acromegaly & Gonadotropic cell. The author has an hindex of 7, co-authored 8 publications receiving 1041 citations.
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Journal ArticleDOI
Natural history of autoimmune thyroiditis.
W. M. G. Tunbridge,M Brewis,J.M. French,D. Appleton,T. Bird,F. Clark,David Evered,J G Evans,Randolph W. Hall,P. A. Smith,J. Stephenson,E. T. Young +11 more
TL;DR: Overt hypothyroidism developed at the rate of 5% a year in women who initially had both raised TSH concentrations and thyroid antibodies, and prophylactic treatment with thyroxine may be justified in women found to have both markers of impending thyroid failure.
Journal ArticleDOI
Effects of growth-hormone release-inhibiting hormone on circulating glucagon, insulin, and growth hormone in normal, diabetic, acromegalic, and hypopituitary patients.
C. H. Mortimer,D. Carr,T. Lind,S.R. Bloom,C.N. Mallinson,Andrew V. Schally,W. M. G. Tunbridge,Lynne Yeomans,David H. Coy,Kastin Aj,G. M. Besser,Randolph W. Hall +11 more
TL;DR: Growth-hormone release-inhibiting hormone impairs the release of glucagon and insulin as well as G.H.-R.I.H. during oral glucose tolerance and intravenous arginine tests; patients with acromegaly, diabetes mellitus, and hypopituitarism aswell as healthy individuals were studied.
Journal ArticleDOI
Luteinizing hormone and follicle stimulating hormone-releasing hormone test in patients with hypothalamic-pituitary-gonadal dysfunction.
C. H. Mortimer,G. M. Besser,A. S. McNEILLY,J. C. Marshall,P. Harsoulis,W. M. G. Tunbridge,A. Gomez-Pan,Randolph W. Hall +7 more
TL;DR: A standard intravenous 100 μg luteinizing hormone/follicle stimulating hormone-releasing hormone (LH/FSH-RH) test was used to assess the pituitary gonadotrophin responses in 155 patients with a variety of diseases of the hypothalamic-pituitary-gonadal axis.
Journal ArticleDOI
Growth Hormone Release Inhibiting Hormone in Acromegaly
G.M. Besser,C. H. Mortimer,D. Carr,Andrew V. Schally,David H. Coy,D. Evered,Abba J. Kastin,W. M. G. Tunbridge,Michael O. Thorner,Reginald Hall +9 more
TL;DR: It is speculated that acromegaly may be primarily a hypothalmic disease due to deficiency of GHRIH resulting in excessive secretion of growth hormone from the pituitary and adenoma formation due to inappropriate and prolonged stimulation of the pituitsary.
Journal ArticleDOI
Interaction between secretion of the gonadotrophins, prolactin, growth hormone, thyrotrophin and corticosteroids in man: the effects of LH FSH-RH, TRH and hypoglycaemia alone and in combination.
TL;DR: It has been shown that TRH releases a small amount of FSH but not LH in male subjects, so that the pituitary reserve for the five anterior pituitsary hormones may be assessed together in under 2 hr.