Wan-Xiang Li

TL;DR: By expressing PVY and CMV‐encoded proteins in a PVX vector, it is shown that the viral suppressors of gene silencing are the HCPro of PVy and the 2b protein of CMV.

TL;DR: This work identifies a distinct mechanism for the amplification of immunity effectors, which together with the requirement for the biogenesis of endogenous siRNAs, may play a role in the emergence and expansion of eukaryotic RDRs.

TL;DR: Investigation of the genetic pathway in Arabidopsis thaliana targeted during infection by cucumber mosaic virus (CMV) 2b protein suggests a model in which 2b inhibits the production of RDR1-dependent viral siRNAs that confer SA-dependent virus resistance by directing non-cell-autonomous antiviral silencing.

TL;DR: This work identifies cooperative action of ARGONAUTE1 and ARGonAUTE2 in virus resistance conferred by 21-nucleotide virus-derived small interfering RNAs (siRNAs) and reveals that 22- nucleotide viral siRNAs do not guide efficient antiviral defense, demonstrating a qualitative difference between 21- and 22-Nucleotide classes ofSiRNAs in RNA silencing.

TL;DR: It is found that although a CMV mutant lacking ORF 2b accumulated in the inoculated cotyledons of cucumber plants, it was unable to spread systemically, demonstrating involvement of 2b in long distance movement.