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Wangjun Fu
Publications - Â 8
Citations - Â 587
Wangjun Fu is an academic researcher. The author has contributed to research in topics: Antibody & Biology. The author has an hindex of 5, co-authored 8 publications receiving 587 citations.
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Journal ArticleDOI
Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron
Zhen Cui,Pan Liu,Nianshuang Wang,Lei Wang,Kaiyue Fan,Qianhui Zhu,Kang-Sheng Wang,Ruihong Chen,Rui Feng,Zijing Jia,Minnan Yang,Ge Xu,Boling Zhu,Wangjun Fu,Tian-jiang Chu,Lei Feng,Yide Wang,Xin-Guo Pei,Peng-Yu Yang,Xiaoliang Sunney Xie,Lei Cao,Yunlong Cao,Xiangxi Wang +22 more
TL;DR: In this article , the structure of the spike (S) from Omicron reveals amino acid substitutions forging interactions that stably maintain an active conformation for receptor recognition, which can be used for the development of broad-spectrum vaccines and therapeutics.
Journal ArticleDOI
Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants
Kang-Sheng Wang,Zijing Jia,Linilin Bao,Lei Wang,Lei Cao,Hang Chi,Yaling Hu,Qianqian Li,Yunjiao Zhou,Yi-Fan Jiang,Qianhui Zhu,Yong-Qiang Deng,Pan Liu,Nan Wang,Lin Wang,Min Liu,Yurong Li,Boling Zhu,Kaiyue Fan,Wangjun Fu,Peng-Yu Yang,Xin-Guo Pei,Zhen Cui,Lili Qin,Pingju Ge,Jiajing Wu,Shuo Liu,Yi-da Chen,Weijin Huang,Qiao-gang Wang,Cheng-Feng Qin,Youchun Wang,Chuan Qin,Xiangxi Wang +33 more
TL;DR: In this article , the authors examined whether sera from individuals who received two or three doses of inactivated SARS-CoV-2 vaccine could neutralize authentic Omicron.
Journal ArticleDOI
Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants
Kang Wang,Zijing Jia,Linilin Bao,Lei Wang,Lei Cao,Hang Chi,Yaling Hu,Qian-Yu Li,Yunjiao Zhou,Yinan Jiang,Qianhui Zhu,Yongqiang Deng,Pan Liu,Nianshuang Wang,Lin Wang,Min Liu,Yurong Li,Boling Zhu,Kaiyue Fan,Wangjun Fu,Peng-Yu Yang,Xin-Guo Pei,Zhen Cui,Lili Qin,Pingju Ge,Jiajing Wu,Shuo Liu,Yi-da Chen,Weijin Huang,Qiao-gang Wang,Cheng-Feng Qin,Youchun Wang,Chuan Qin,Xiangxi Wang +33 more
TL;DR: In this paper , the authors examined whether sera from individuals who received two or three doses of inactivated SARS-CoV-2 vaccine could neutralize authentic Omicron.
Journal ArticleDOI
Characterization of the enhanced infectivity and antibody evasion of Omicron BA.2.75
Yunlong Cao,Weiliang Song,Lei Wang,Pan Liu,Can Yue,F. Jian,Yuanling Yu,Ayijiang Yisimayi,Peng Wang,Yao Wang,Qianhui Zhu,Jie Deng,Wangjun Fu,Lingling Yu,Na Zhang,Jing Wang,T. Xiao,Ran An,Lu Liu,Siyuan Yang,Xiaowei Niu,Qingqing Gu,Fei Shao,Xiaohua Hao,Ronghua Jin,Youchun Wang,Xiaoliang Sunney Xie,Xiangxi Wang +27 more
TL;DR: Wang et al. as discussed by the authors showed that BA.2.75 exhibits substantially higher affinity for host receptor angiotensin-converting enzyme 2 (ACE2) than BA.4/BA.5 and other variants.
Journal ArticleDOI
Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages
Lei Wang,Wangjun Fu,Linlin Bao,Zijing Jia,YuXia Zhang,Yunjiao Zhou,Wei Wu,Jianbo Wu,Qianqian Zhang,Yidan Gao,Kang Wang,Qiao-gang Wang,Chuan Qin,Xiangxi Wang +13 more
TL;DR: Omicron, with a dramatically increased infectivity and enhanced transmissibility, is rapidly replacing the Delta variant and is poised to become a predominately prevalent strain in more than 110 countries since it was reported in South Africa at the end of 2021.