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Shuo Liu
Publications - 39
Citations - 2416
Shuo Liu is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 14 publications receiving 909 citations.
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Journal ArticleDOI
The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity.
Qianqian Li,Jiajing Wu,Jianhui Nie,Li Zhang,Huan Hao,Shuo Liu,Chenyan Zhao,Qi Zhang,Huan Liu,Lingling Nie,Haiyang Qin,Meng Wang,Qiong Lu,Xiaoyu Li,Qiyu Sun,Junkai Liu,Linqi Zhang,Xuguang Li,Weijin Huang,Youchun Wang +19 more
TL;DR: Most variants with amino acid change at receptor binding domain were less infectious but variants including A475V, L452R, V483A and F490L became resistant to some neutralizing antibodies, while deletion of both N331 and N343 glycosylation drastically reduced infectivity, revealing the importance of gly cosylation for viral infectivity.
Journal ArticleDOI
SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape.
Qianqian Li,Jianhui Nie,Jiajing Wu,Li Zhang,Ruxia Ding,Haixin Wang,Yue Zhang,Tao Li,Shuo Liu,Mengyi Zhang,Chenyan Zhao,Huan Liu,Lingling Nie,Haiyang Qin,Meng Wang,Qiong Lu,Xiaoyu Li,Junkai Liu,Haoyu Liang,Yi Shi,Yuelei Shen,Liangzhi Xie,Linqi Zhang,Xiaowang Qu,Wenbo Xu,Weijin Huang,Youchun Wang +26 more
TL;DR: In this article, experiments with 18 pseudotyped viruses showed that the 501Y.V2 variants do not confer increased infectivity in multiple cell types except for murine ACE2-overexpressing cells, where a substantial increase in infectivity was observed.
Journal ArticleDOI
Circular RNA vaccines against SARS-CoV-2 and emerging variants
Liang Qu,Zong Yi Yi,Yong Shen,Liangru Lin,Feng Chen,Yiyuan Xu,Zeguang Wu,H. Tang,Xiaoxue Zhang,Feng Tian,Chunhui Wang,Xia Xiao,Xiaojing Dong,Li Guo,Shuaiyao Lu,Chen Yang,Cong Tang,Yun jeong Yang,Wenhai Yu,Junbin Wang,Yanan Zhou,Q. Huang,Ayijiang Yisimayi,Shuo Liu,Weijin Huang,Yunlong Cao,Youchun Wang,Zhuo Zhou,Xiaozhong Peng,Jianwei Wang,Xiaoliang Sunney Xie,Wensheng Wei +31 more
TL;DR: In this paper , a circular RNA (circRNA) vaccine that elicited potent neutralizing antibodies and T cell responses by expressing the trimeric RBD of the spike protein, providing robust protection against SARS-CoV-2 in both mice and rhesus macaques.
Journal ArticleDOI
Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants
Kang-Sheng Wang,Zijing Jia,Linilin Bao,Lei Wang,Lei Cao,Hang Chi,Yaling Hu,Qianqian Li,Yunjiao Zhou,Yi-Fan Jiang,Qianhui Zhu,Yong-Qiang Deng,Pan Liu,Nan Wang,Lin Wang,Min Liu,Yurong Li,Boling Zhu,Kaiyue Fan,Wangjun Fu,Peng-Yu Yang,Xin-Guo Pei,Zhen Cui,Lili Qin,Pingju Ge,Jiajing Wu,Shuo Liu,Yi-da Chen,Weijin Huang,Qiao-gang Wang,Cheng-Feng Qin,Youchun Wang,Chuan Qin,Xiangxi Wang +33 more
TL;DR: In this article , the authors examined whether sera from individuals who received two or three doses of inactivated SARS-CoV-2 vaccine could neutralize authentic Omicron.
Journal ArticleDOI
Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants
Kang Wang,Zijing Jia,Linilin Bao,Lei Wang,Lei Cao,Hang Chi,Yaling Hu,Qian-Yu Li,Yunjiao Zhou,Yinan Jiang,Qianhui Zhu,Yongqiang Deng,Pan Liu,Nianshuang Wang,Lin Wang,Min Liu,Yurong Li,Boling Zhu,Kaiyue Fan,Wangjun Fu,Peng-Yu Yang,Xin-Guo Pei,Zhen Cui,Lili Qin,Pingju Ge,Jiajing Wu,Shuo Liu,Yi-da Chen,Weijin Huang,Qiao-gang Wang,Cheng-Feng Qin,Youchun Wang,Chuan Qin,Xiangxi Wang +33 more
TL;DR: In this paper , the authors examined whether sera from individuals who received two or three doses of inactivated SARS-CoV-2 vaccine could neutralize authentic Omicron.