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Wangyan Zhou
Researcher at University of South China
Publications - 5
Citations - 14
Wangyan Zhou is an academic researcher from University of South China. The author has contributed to research in topics: Medicine & Cancer research. The author has an hindex of 1, co-authored 1 publications receiving 5 citations.
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Journal ArticleDOI
Co-Occurring Alterations of ERBB2 Exon 20 Insertion in Non-Small Cell Lung Cancer (NSCLC) and the Potential Indicator of Response to Afatinib.
Bo Yuan,Jun Zhao,Chengzhi Zhou,Xiumei Wang,Bo Zhu,Minglei Zhuo,Xilin Dong,Jiemei Feng,Cuihua Yi,Yunpeng Yang,Hua Zhang,Wangyan Zhou,Zhengtang Chen,Sheng Yang,Xinghao Ai,Kehe Chen,Xuefan Cui,Difa Liu,Chunmei Shi,Wei Wu,Yanjun Zhang,Lianpeng Chang,Jin Li,Rongrong Chen,Shuanying Yang +24 more
TL;DR: The data revealed co-occurring TP53 represent an unfavorable prognosis of patients with ERBB2ex20ins, emphasizing the more valuable role of the co-mutation patterns than insertion-site subtypes in predicting prog outlook of this group of patients.
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Let-7c-5p Restrains Cell Growth and Induces Apoptosis of Lung Adenocarcinoma Cells via Targeting ESPL1
TL;DR: It was posited that let-7c-5p/ESPL1 may be underlying therapeutic targets of LUAD, which was associated with poor prognosis and downregulated in LUAD cells, and played a suppressive role inLUAD malignant development while reversed by ESPL1.
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Comprehensive Analysis of CDK1-Associated ceRNA Network Revealing the Key Pathways LINC00460/LINC00525-Hsa-Mir-338-FAM111/ZWINT as Prognostic Biomarkers in Lung Adenocarcinoma Combined with Experiments
Wen Li,Shanwei Feng,Hao Wu,Jing Deng,Wangyan Zhou,Ming Xi Jia,Yi Shi,Liang Ma,Xiaoxi Zeng,Zavuga Zuberi,Da Fu,Xiang Liu,Zhu Chen +12 more
TL;DR: A CDK1-related ceRNA network was constructed and revealed the LINC00460/LINC00525-hsa-mir-338-FAM111/ZWINT pathways as potential diagnostic biomarkers or therapeutic targets of LUAD.
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Identification of EGFR-Related LINC00460/mir-338-3p/MCM4 Regulatory Axis as Diagnostic and Prognostic Biomarker of Lung Adenocarcinoma Based on Comprehensive Bioinformatics Analysis and Experimental Validation
Ming Xi Jia,Shanshan Feng,Feng Cao,Jing Deng,Wen Ding Li,Wangyan Zhou,Xiangtao Liu,Weidong Bai +7 more
TL;DR: The LINC00460—mir-338-3p—MCM4 ceRNA network plays an important role in the diagnosis and prognosis of LUAD and is expected to serve as a diagnostic, prognostic and drug target for LUAD.
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Clinical significance of securin expression in solid cancers: A PRISMA-compliant meta-analysis of published studies and bioinformatics analysis based on TCGA dataset
TL;DR: The study indicated that securin overexpression was positively associated with metastasis and inversely related to the prognosis of patients with solid cancers, however, additional high-quality studies should be conducted to validate these findings.