J
Jin Li
Researcher at Guangzhou Medical University
Publications - 33
Citations - 654
Jin Li is an academic researcher from Guangzhou Medical University. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 12, co-authored 27 publications receiving 480 citations. Previous affiliations of Jin Li include Cardiff University.
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Journal ArticleDOI
Frequent alterations in cytoskeleton remodelling genes in primary and metastatic lung adenocarcinomas.
Kui Wu,Xin Zhang,Fuqiang Li,Dakai Xiao,Yong Hou,Shida Zhu,Dongbing Liu,Xiaofei Ye,Mingzhi Ye,Jie Yang,Shao Libin,Hui Pan,Na Lu,Yuan Yu,Liping Liu,Jin Li,Liyan Huang,Hailing Tang,Qiuhua Deng,Zheng Yue,Lihua Peng,Geng Liu,Xia Gu,Ping He,Yingying Gu,Weixuan Lin,Huiming He,Guoyun Xie,Han Liang,Na An,Hui Wang,Manuel R. Teixeira,Joana Vieira,Wenhua Liang,Xin Zhao,Zhiyu Peng,Feng Mu,Xiuqing Zhang,Xun Xu,Huanming Yang,Karsten Kristiansen,Jian Wang,Nanshan Zhong,Jun Wang,Qiang Pan-Hammarström,Jianxing He +45 more
TL;DR: This study represents the first large-scale sequencing effort on lung adenocarcinoma in Asian patients and provides a comprehensive mutational landscape for both primary and metastatic tumours, and may form a basis for personalized medical care.
Journal ArticleDOI
PSCA and MUC1 in non-small-cell lung cancer as targets of chimeric antigen receptor T cells.
Xinru Wei,Yunxin Lai,Jin Li,Le Qin,Youdi Xu,Ruocong Zhao,Baiheng Li,Lin Simiao,Suna Wang,Qiting Wu,Qiubin Liang,Muyun Peng,Fenglei Yu,Yangqiu Li,Xu-Chao Zhang,Yi-Long Wu,Pentao Liu,Duanqing Pei,Yao Yao,Peng Li +19 more
TL;DR: It is demonstrated that PSCA and MUC1 are both promising CAR T cell targets in NSCLC and that the combinatorial targeting of these antigens could further enhance the antitumor efficacy of CAR T cells.
Journal ArticleDOI
Expression of gamma-aminobutyric acid receptors on neoplastic growth and prediction of prognosis in non-small cell lung cancer
Xiaoxue Zhang,Rong Zhang,Yuanjie Zheng,Jianfei Shen,Dakai Xiao,Jin Li,Xiaoshun Shi,Liyan Huang,Hailing Tang,Jun Liu,Jianxing He,Haibo Zhang +11 more
TL;DR: The pattern of GABA receptor gene phenotype expression may be involved in the regulation of tumorigenesis and may also serve as valuable prognostic markers for NSCLC.
Journal ArticleDOI
Bone morphogenetic protein-10 (BMP-10) inhibits aggressiveness of breast cancer cells and correlates with poor prognosis in breast cancer
Lin Ye,Sivan M. Bokobza,Jin Li,Muhammad Moazzam,Jinfeng Chen,Jinfeng Chen,Robert E. Mansel,Wen Jiang +7 more
TL;DR: The overexpression of BMP‐10 has broad inhibitory effects on the in vitro growth, invasion, and motility of breast cancer cells, and decreased expression correlates to poor prognosis and disease progression, particularly the lymphatic and bone metastasis.
Journal ArticleDOI
Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments.
Wei Ye,Zhiwu Jiang,Guan Xiong Li,Yiren Xiao,Lin Simiao,Yunxin Lai,Suna Wang,Baiheng Li,Bei Jia,Yin Li,Zhi Liang Huang,Jin Li,Fenglan Feng,Shuhua Li,Huihui Yao,Zixia Liu,Su Cao,Lin Xu,Yangqiu Li,Donghai Wu,Lingwen Zeng,Mei Zhong,Pentao Liu,Zhe Sheng Wen,Bing Xu,Yao Yao,Duanqing Pei,Peng Li +27 more
TL;DR: A tumor engraftment index (TEI) was developed to reflect the immunodeficiency of a mouse strain and validated that the NOD-scid-IL2Rg−/− (NSI) mice, which had the highest TEI score, were more suitable for xenograft and allograft experiments using multiple functional assays.