Wanjun Qi

TL;DR: It is reported that FUNDC1, an integral mitochondrial outer-membrane protein, is a receptor for hypoxia-induced mitophagy, and its findings offer insights into mitochondrial quality control in mammalian cells.

TL;DR: In this article , the authors discover that depletion of the phosphate transceptor Pho84 across multiple fungal species encountered a substantial cost in gastrointestinal colonization, but this did not translate into enhanced pathogenicity.

TL;DR: Findings unveil that a T. gondii-derived protein is able to promote inflammasome activation, and further study of ROP7 will deepen the understanding of host innate immunity to parasites.

TL;DR: In this paper , the specific EGFR inhibitor osimertinib mesylate (OSI) was found to potentiate azole efficacy against diverse fungal pathogens and overcomes azole resistance.

TL;DR: Results show that provision of cells with GPC as phosphate source alleviates hypersensitivity of pho84∆/∆ mutants to osmotic, oxidative, and cell wall stress and indicates that C. albicans can utilize the abundant lipid metabolite, GPC, via at least two metabolic pathways to promote its growth and survival in the human host.