Wei Chen

TL;DR: Patients with high-risk resected colon cancer obtain benefit from FU-based therapy across subsets of age, sex, location, T stage, nodal status, and grade, which may improve patients' and physicians' understanding of the potential benefits of adjuvant therapy.

TL;DR: The results suggest that the loss of let-7 mediated increased expression of EZH2 contributes to PCa aggressiveness, which could be attenuated by BR-DIM treatment, and thus BR- DIM is likely to have clinical impact.

TL;DR: A role ofmiR-200s in PGI/AMF-induced EMT is suggested and approaches for upregulation of miR- 200s could be a novel therapeutic strategy for the treatment of highly invasive breast cancer.

TL;DR: Variation in the aberrant expression patterns at the invasive tumor front indicates the role of EMT markers in tumor invasion and suggests that Notch-1 could play a role in PCa bone metastasis.

TL;DR: The results suggest that identifying and validating the expression of microRNAs in newly diagnosed patients could serve as potential biomarker for tumor aggressiveness, and such miRNAs could be useful for the screening of high-risk patients, and may also serve as targets for future drug development.