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Weiming Yan
Researcher at Huazhong University of Science and Technology
Publications - 17
Citations - 3474
Weiming Yan is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: FGL2 & Virus. The author has an hindex of 8, co-authored 16 publications receiving 2640 citations. Previous affiliations of Weiming Yan include Tongji Medical College.
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Journal ArticleDOI
Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study.
Tao Chen,Di Wu,Huilong Chen,Weiming Yan,Danlei Yang,Guang Chen,Ke Ma,Dong Xu,Haijing Yu,Hongwu Wang,Tao Wang,Wei Guo,Jia Chen,Chen Ding,Xiaoping Zhang,Jiaquan Huang,Meifang Han,Shusheng Li,Xiaoping Luo,Jianping Zhao,Qin Ning +20 more
TL;DR: Severe acute respiratory syndrome coronavirus 2 infection can cause both pulmonary and systemic inflammation, leading to multi-organ dysfunction in patients at high risk, including patients with cardiovascular comorbidity.
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Non-alcoholic hepatic steatosis attenuates hepatitis B virus replication in an HBV-immunocompetent mouse model.
TL;DR: In an HBV-immunocompetent mouse model, non-alcoholic hepatic steatosis inhibited HBV replication, as indicated by the reduction of HBV DNA andHBV-related antigens.
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Novel mfgl2 antisense plasmid inhibits murine fgl2 expression and ameliorates murine hepatitis virus type 3-induced fulminant hepatitis in BALB/cJ mice.
TL;DR: This study may provide an effective way to interfere with the potential therapeutic target fgl2 gene for fulminant viral hepatitis and other diseases with similar pathological characteristics of microcirculation disorders, including acute rejection of xeno- or allograft transplantation and fetal loss syndrome.
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The Nucleocapsid Protein of SARS-CoV Induces Transcription of hfgl2 Prothrombinase Gene Dependent on C/EBP Alpha
Meifang Han,Weiming Yan,Yuancheng Huang,Huaning Yao,Zhanhui Wang,Dong Xi,Weina Li,Yaoyong Zhou,Jinlin Hou,Xiaoping Luo,Qin Ning +10 more
TL;DR: N protein of SARS-CoV induced hfgl2 gene transcription dependent on the transcription factor C/EBP alpha, which maybe contribute to the development of thrombosis in SARS.
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Sequential combination therapy with interferon, interleukin-2 and therapeutic vaccine in entecavir-suppressed chronic hepatitis B patients: the Endeavor study.
Di Wu,Peng Wang,Meifang Han,Yongping Chen,Xinyue Chen,Qi Xia,Weiming Yan,Xiaoyang Wan,Chuanlong Zhu,Qing Xie,Jiaji Jiang,Lai Wei,Deming Tan,Xiaoguang Dou,Yanyan Yu,Jinlin Hou,Xiaoping Luo,Qin Ning +17 more
TL;DR: For ETV-suppressed patients, particularly those with low baseline HBsAg levels, combination therapy with IFN and other immunomodulators may enhanceHBsAg loss, while successful response correlates with partial restoration of NK cells and Tregs.