W
Weitao Huang
Researcher at LSU Health Sciences Center New Orleans
Publications - 20
Citations - 3241
Weitao Huang is an academic researcher from LSU Health Sciences Center New Orleans. The author has contributed to research in topics: Haematopoiesis & Proinflammatory cytokine. The author has an hindex of 11, co-authored 19 publications receiving 3115 citations. Previous affiliations of Weitao Huang include Louisiana State University.
Papers
More filters
Journal ArticleDOI
Requirement of Interleukin 17 Receptor Signaling for Lung Cxc Chemokine and Granulocyte Colony-Stimulating Factor Expression, Neutrophil Recruitment, and Host Defense
Peng Ye,Fred H. Rodriguez,Suzanne T. Kanaly,Kim L. Stocking,Jill R. Schurr,Paul Schwarzenberger,Peter Oliver,Weitao Huang,Ping Zhang,Jason Zhang,Judd E. Shellito,G. J. Bagby,Steve Nelson,Keith Charrier,Jacques J. Peschon,Jay K. Kolls +15 more
TL;DR: Impaired IL-17R signaling is supported as a potential mechanism by which deficiency of CD4 lymphocytes predisposes to bacterial pneumonia.
Journal ArticleDOI
Requirement of Interleukin-17A for Systemic Anti-Candida albicans Host Defense in Mice
TL;DR: The data suggest that the mIL- 17A/mIL-17AR system is required for normal fungal host defense in vivo, and IL-17A could have potential as a therapeutic cytokine for systemic C. albicans infections in immunocompromised patients with cancer or advanced acquired immunodeficiency syndrome.
Journal Article
IL-17 Stimulates Granulopoiesis in Mice: Use of an Alternate, Novel Gene Therapy-Derived Method for In Vivo Evaluation of Cytokines
Paul Schwarzenberger,V. La Russa,Alan M. Miller,Peng Ye,Weitao Huang,A. Zieske,Steve Nelson,G. J. Bagby,David A. Stoltz,R. L. Mynatt,M. Spriggs,Jay K. Kolls +11 more
TL;DR: In this article, Adenovirus-mediated gene transfer of the murine IL-17 cDNA targeted to the liver (5 x 10(9) plaque-forming units (PFU) intravenous) resulted in a transiently transgenic phenotype, with dramatic effects on in vivo granulopoiesis.
Journal ArticleDOI
Requirement of endogenous stem cell factor and granulocyte-colony-stimulating factor for IL-17-mediated granulopoiesis.
Paul Schwarzenberger,Weitao Huang,Peng Ye,Peter Oliver,Misty Manuel,Zili Zhang,Gregory J. Bagby,Steve Nelson,Jay K. Kolls +8 more
TL;DR: There remained a significant SCF/G-CSF-independent effect of IL-17 on splenic granulopoiesis, resulting in a preservation of mature circulating granulocytes, which may have potential for therapeutic development.
Journal ArticleDOI
Requirement of IL-17 Receptor Signaling in Radiation-Resistant Cells in the Joint for Full Progression of Destructive Synovitis
E Lubberts,E Lubberts,Paul Schwarzenberger,Weitao Huang,Jill R. Schurr,Jacques J. Peschon,Wim B. van den Berg,Jay K. Kolls +7 more
TL;DR: It is reported that IL-17R signaling is required in radiation-resistant cells in the joint for full progression of chronic synovitis and bone erosion and chimeric mice of host IL- 17R−/− and donor wt BM cells were protected from chronic destructive arthritis similar to wt→wt chimeras.