W
Wen Sun
Researcher at University of Science and Technology of China
Publications - 39
Citations - 1149
Wen Sun is an academic researcher from University of Science and Technology of China. The author has contributed to research in topics: Stroke & Modified Rankin Scale. The author has an hindex of 12, co-authored 39 publications receiving 588 citations. Previous affiliations of Wen Sun include Nanjing Medical University & Shanghai Jiao Tong University.
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Journal ArticleDOI
Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial.
Xinfeng Liu,Xinfeng Liu,Qiliang Dai,Ruidong Ye,Wenjie Zi,Wenjie Zi,Yuxiu Liu,Huaiming Wang,Wusheng Zhu,Minmin Ma,Qin Yin,Min Li,Xinying Fan,Wen Sun,Yunfei Han,Qiushi Lv,Rui Liu,Dong Yang,Zhonghua Shi,Dequan Zheng,Xiaorong Deng,Yue Wan,Zhen Wang,Yu Geng,Xingyu Chen,Zhiming Zhou,Geng Liao,Ping Jin,Yumin Liu,Xintong Liu,Meng Zhang,Feng Zhou,Hongchao Shi,Yunfeng Zhang,Fuqiang Guo,Congguo Yin,Guozhong Niu,Mei Zhang,Xueli Cai,Qiyi Zhu,Zhonglun Chen,Yingchun Liang,Bing Li,Min Lin,Wei Wang,Haowen Xu,Xinmin Fu,Wenhua Liu,Xiguang Tian,Zili Gong,Haicun Shi,Chuanming Wang,Penghua Lv,Zhonghai Tao,Liangfu Zhu,Shiquan Yang,Wei Hu,Pingzhou Jiang,David S Liebeskind,Vitor Mendes Pereira,Thomas W. Leung,Bernard Yan,Stephen M. Davis,Gelin Xu,Raul G Nogueira,Yunyun Xiong,Zongjie Shi,Weihong Zheng,Xianjun Huang,Yong Liu,Huagang Li,Kaifu Ke,Shu Yang,Hang Lin,Wei Dan,Lin Chen,Liangqun Rong,Shuiping Wang,Jin Fan,Chengming Xing,Haifeng Li,Weiming Yang,Changqing Wang,Yong Zhang,Xiaobo Li,Vitor Pereira,David Liebeskind,Raul G. Nogueira +87 more
TL;DR: There was no evidence of a difference in favourable outcomes of patients receiving endovascular therapy compared with those receiving standard medical therapy alone, and the trial was terminated early after 131 patients had been randomly assigned because of high crossover rate and poor recruitment.
Journal ArticleDOI
Erianin induces G2/M-phase arrest, apoptosis, and autophagy via the ROS/JNK signaling pathway in human osteosarcoma cells in vitro and in vivo.
He-xiao Wang,He-xiao Wang,Tao Zhang,Wen Sun,Z Wang,Dongqing Zuo,Dongqing Zuo,Zifei Zhou,Zifei Zhou,Suoyuan Li,Jianrong Xu,Fei Yin,Ying-qi Hua,Zhengdong Cai +13 more
TL;DR: Erianin may be a promising agent for anticancer therapy against OS through induced cell cycle G2/M-phase arrest, apoptosis, and autophagy via the ROS/JNK signaling pathway in human OS.
Journal ArticleDOI
TREM-1 Exacerbates Neuroinflammatory Injury via NLRP3 Inflammasome-Mediated Pyroptosis in Experimental Subarachnoid Hemorrhage
Pengfei Xu,Pengfei Xu,Ye Hong,Yi Xie,Kang Yuan,Juanji Li,Rui Sun,Xiaohao Zhang,Xiaolei Shi,Rongrong Li,Jiaonan Wu,Xinfeng Liu,Xinfeng Liu,Wei Hu,Wen Sun +14 more
TL;DR: Mechanistically, both in vivo and in vitro, it is depicted that TREM-1 can trigger microglial pyroptosis via activating NLRP3 inflammasome, and inhibition with LP17 improved neurological deficits, mitigated brain water content, and preserved brain-blood barrier integrity 24 h after SAH.
Journal ArticleDOI
Dynamic change of neutrophil to lymphocyte ratio and hemorrhagic transformation after thrombolysis in stroke.
Zhiliang Guo,Zhiliang Guo,Shuhong Yu,Lulu Xiao,Xin Chen,Ruidong Ye,Ping Zheng,Qiliang Dai,Wen Sun,Changsheng Zhou,Shuiping Wang,Wusheng Zhu,Xinfeng Liu +12 more
TL;DR: NLR is a dynamic variable, and its variation is associated with HT after thrombolysis in stroke patients, and the NLR was higher in patients who developed PH or sICH at 3–6, 12–18, and 36–48 h after IVT.
Journal ArticleDOI
Distal hyperintense vessels on FLAIR: a prognostic indicator of acute ischemic stroke.
Xianjun Huang,Wenhua Liu,Wusheng Zhu,Guanzhong Ni,Wen Sun,Minmin Ma,Zhiming Zhou,Qizhang Wang,Gelin Xu,Xinfeng Liu +9 more
TL;DR: Examining the prognostic value of HVs in AIS revealed that distal HVs are an independent predictor of a favorable outcome at 90 days and was correlated with the presence of LMCs.