Geng Liao

TL;DR: There was no evidence of a difference in favourable outcomes of patients receiving endovascular therapy compared with those receiving standard medical therapy alone, and the trial was terminated early after 131 patients had been randomly assigned because of high crossover rate and poor recruitment.

TL;DR: In a trial involving Chinese patients with basilar-artery occlusion, approximately one third of whom received intravenous thrombolysis, endovascular thrombectomy within 12 hours after stroke onset led to better functional outcomes at 90 days than best medical care but was associated with procedural complications and intracerebral hemorrhage.

TL;DR: The clinical outcomes of patients with stroke with large vessel occlusion treated with direct endovascular thrombectomy within 4·5 h would be non-inferior compared with the outcomes of those treated with standard bridging therapy, as well as the intention-to-treat population, were hypothesized.

TL;DR: In this article , the role of endovascular therapy for acute stroke with a large infarction has not been extensively studied in differing populations, and the authors conducted a multicenter, prospective, open-label, randomized trial in China involving patients with acute large-vessel occlusion in the anterior circulation and an Alberta Stroke Program Early Computed Tomography Score of 3 to 5 (range, 0 to 10, with lower values indicating larger infarctions) or an infarct-core volume of 70 to 100 ml.

TL;DR: In this real-world study, EVT was associated with significantly better functional outcomes and survival at 90 days and well-designed randomized studies comparing EVT with BMM in the acute BAO are needed.