Haowen Xu

TL;DR: There was no evidence of a difference in favourable outcomes of patients receiving endovascular therapy compared with those receiving standard medical therapy alone, and the trial was terminated early after 131 patients had been randomly assigned because of high crossover rate and poor recruitment.

TL;DR: Incidence of SICH after thrombectomy is higher in Asian patients with acute ischemic stroke, and Cardioembolic stroke, poor collateral circulation, delayed endovascular treatment, multiple passes with stent retriever device, lower pretreatment Alberta Stroke Program Early Computed Tomography Score, higher baseline neutrophil ratio may increase the risk of Sich.

TL;DR: Evidence in real world to support the performance of EVT in acute anterior circulation stroke patients in Chinese population is provided, and patients with small infarct core, successful recanalization, good collateral status, and short treatment delay without sICH or pneumonia may benefit from EVT.

TL;DR: More than three retriever passes may increase the rate of recanalization, but not the likelihood of favorable functional outcomes in ischemic stroke patients treated with mechanical thrombectomy; Notably, multiple retriver passes may also increase the risk of intracranial hemorrhage.

TL;DR: Overall, eptifibatide shows potential as a periprocedural adjunctive antithrombotic therapy when combined with mechanical thrombectomy and did not raise major safety concerns and showed a trend of better efficacy outcomes compared with MT alone.