Wengang Li

TL;DR: The frontline nurses experienced a variety of mental health challenges, especially burnout and fear, which warrant attention and support from policymakers and future interventions at the national and organisational levels are needed.

TL;DR: In this paper, the authors reported that Sulindac, an NSAID, induces apoptosis by binding to retinoid X receptor-alpha (RXRalpha) in several cancer cell lines and primary tumors.

TL;DR: It is demonstrated that Nur77 acts to promote the growth and survival of colon cancer cells and serves as an important mediator of the Wnt/β‐catenin and AP‐1 signaling pathways.

TL;DR: Overexpression of RARgamma plays a role in the growth of HCC cells through nongenomic activation of the PI3K/Akt and NF-kappaB signaling pathways, and results show that levels of R ARgamma were significantly elevated in tumor tissues from a majority of human hepatocellular carcinoma (HCC) and in HCC cell lines.

TL;DR: The findings demonstrate that GSK-3β is a disruptor of retinoid signalling and a new resistant factor of sorafenib in HCC and may be a promising strategy for HCC treatment in clinic.