L
Luoling Xu
Researcher at National Institutes of Health
Publications - 9
Citations - 1262
Luoling Xu is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Chemokine & Chemotaxis. The author has an hindex of 7, co-authored 9 publications receiving 1217 citations. Previous affiliations of Luoling Xu include University of Western Ontario.
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Journal ArticleDOI
Identification of Defensin-1, Defensin-2, and CAP37/Azurocidin as T-cell Chemoattractant Proteins Released from Interleukin-8-stimulated Neutrophils (∗)
Oleg Chertov,Dennis F. Michiel,Luoling Xu,Ji Ming Wang,Kenji Tani,William J. Murphy,Dan L. Longo,Dennis D. Taub,Joost J. Oppenheim +8 more
TL;DR: The antimicrobial proteins, CAP37/azurocidin and defensins H NP-1 and HNP-2, are identified as potent neutrophil-derived chemoattractants for T-cells, which represent primordial antimicrobial peptides which may have evolved into acute inflammatory cell-derived signals that mobilize immunocompetent T- cells and other inflammatory cells.
Journal Article
A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion.
Luoling Xu,Raffaele Badolato,William J. Murphy,Dan L. Longo,Miriam R. Anver,Shirley Hale,Joost J. Oppenheim,Ji Ming Wang +7 more
TL;DR: It is shown that recombinant human (rh) SAA also induces directional migration of T cells in vitro, and may play an important role in recruiting T lymphocytes, as well as neutrophils and monocytes into inflammatory lesions.
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Monocyte Chemotactic Protein-3 (MCP3) Interacts with Multiple Leukocyte Receptors C-C CKR1, A RECEPTOR FOR MACROPHAGE INFLAMMATORY PROTEIN-1α/RANTES, IS ALSO A FUNCTIONAL RECEPTOR FOR MCP3
TL;DR: Since MCP3 has been reported to use MCP1 receptor(s), this work's results with transfected 293 cells expressing only C-C CKR1 clearly establish that C-MIP1α or macrophage inflammatory protein-1α (Mip1α)/Rantes receptor is also a functional receptor for M CP3.
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Granulocyte-Colony Stimulating Factor and Lipopolysaccharide Regulate the Expression of Interleukin 8 Receptors on Polymorphonuclear Leukocytes
Andrew R. Lloyd,Arya Biragyn,J A Johnston,Dennis D. Taub,Luoling Xu,Luoling Xu,Dennis F. Michiel,H Sprenger,Joost J. Oppenheim,David J. Kelvin,David J. Kelvin +10 more
TL;DR: The two types of IL-8 receptor differ in their cellular distribution and are regulated in response to cytokines and LPS, which may be important in the in vivo control of PMN effector functions in inflammation.
Journal ArticleDOI
In Situ Replication of Immediate Dendritic Cell (DC) Precursors Contributes to Conventional DC Homeostasis in Lymphoid Tissue
Jun Diao,Erin Winter,Claude Cantin,Wenhao Chen,Luoling Xu,David J. Kelvin,Jim Phillips,Jim Phillips,Mark S. Cattral +8 more
TL;DR: It is shown that mouse CD11c+ MHC class II−lineage− cells are immediate precursors of conventional DC and are widely distributed in both bone marrow and lymphoid tissues and highlight the importance of in situ replication of immediate DCp and DC in maintaining conventional DC populations.