W
Wilfried Schgoer
Researcher at Innsbruck Medical University
Publications - 36
Citations - 1017
Wilfried Schgoer is an academic researcher from Innsbruck Medical University. The author has contributed to research in topics: Reverse cholesterol transport & Cholesterol. The author has an hindex of 18, co-authored 34 publications receiving 865 citations.
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Journal ArticleDOI
Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site
Emir Hadzijusufovic,Emir Hadzijusufovic,Karin Albrecht-Schgoer,Kilian Huber,Gregor Hoermann,Florian Grebien,Gregor Eisenwort,Wilfried Schgoer,Susanne Herndlhofer,Christoph Kaun,Markus Theurl,Wolfgang R. Sperr,Uwe Rix,Irina Sadovnik,Bernd Jilma,Gerit-Holger Schernthaner,Johann Wojta,Dominik Wolf,Giulio Superti-Furga,Rudolf Kirchmair,Peter Valent +20 more
TL;DR: Together, Nilotinib exerts direct pro-atherogenic and anti-angiogenic effects on vascular endothelial cells, which may contribute to development of AOD in patients with CML.
Journal ArticleDOI
The Neuropeptide Catestatin Acts As a Novel Angiogenic Cytokine via a Basic Fibroblast Growth Factor–Dependent Mechanism
Markus Theurl,Wilfried Schgoer,Karin Albrecht,Johannes Jeschke,Margot Egger,Arno Beer,Danijela Vasiljevic,Song Rong,Anna Maria Wolf,Ferdinand H. Bahlmann,Josef R. Patsch,Dominik Wolf,Peter Schratzberger,Sushil K. Mahata,Rudolf Kirchmair +14 more
TL;DR: Catestatin acts as a novel angiogenic cytokine via a basic fibroblast growth factor–dependent mechanism, indicating induction of arteriogenesis and postnatal vasculogenesis.
Journal ArticleDOI
The Angiogenic Factor Secretoneurin Induces Coronary Angiogenesis in a Model of Myocardial Infarction by Stimulation of Vascular Endothelial Growth Factor Signaling in Endothelial Cells
Karin Albrecht-Schgoer,Wilfried Schgoer,Johannes Holfeld,Markus Theurl,Dominik Wiedemann,Christina Maria Steger,Rajesh Gupta,Severin Semsroth,Reiner Fischer-Colbrie,Arno Beer,Ursula Stanzl,Eva Huber,Sol Misener,Daniel Dejaco,Raj Kishore,Otmar Pachinger,Michael Grimm,Nikolaos Bonaros,Rudolf Kirchmair +18 more
TL;DR: In vivo findings indicate that secretoneurin may be a promising therapeutic tool in ischemic heart disease by enhancing binding of VEGF to low-affinity binding sites and neuropilin-1 and stimulates further growth factor receptors like fibroblast growth factor receptor-3.
Journal ArticleDOI
Monocyte migration: a novel effect and signaling pathways of catestatin.
Margot Egger,Arno Beer,Markus Theurl,Wilfried Schgoer,Benjamin Hotter,Tobias Tatarczyk,Danijela Vasiljevic,Silke Frauscher,Josef Marksteiner,Josef R. Patsch,Peter Schratzberger,Angela Djanani,Sushil K. Mahata,Rudolf Kirchmair +13 more
TL;DR: It is demonstrated that catestatin dose-dependently stimulates chemotaxis of human peripheral blood monocytes, exhibiting its maximal effect at a concentration of 1 nM comparable to the established chemoattractant formylated peptide Met-Leu-Phe (fMLP).
Journal ArticleDOI
Hypoxia up-regulates the angiogenic cytokine secretoneurin via an HIF-1α- and basic FGF-dependent pathway in muscle cells
Margot Egger,Wilfried Schgoer,Arno Beer,Johannes Jeschke,Johannes Leierer,Markus Theurl,Silke Frauscher,Oren M. Tepper,Andreas Niederwanger,Andreas Ritsch,Marianne Kearney,Julia Wanschitz,Geoffrey C. Gurtner,Reiner Fischer-Colbrie,Guenter Weiss,Hildegunde Piza-Katzer,Douglas W. Losordo,Josef R. Patsch,Peter Schratzberger,Rudolf Kirchmair +19 more
TL;DR: Hypoxia up‐regulates the angiogenic cytokine secretoneurin via an HIF‐1α‐ and basic FGF‐dependent pathway in muscle cells by hypoxia‐inducible factor‐1 α and basic fibroblast growth factor‐dependent mechanisms.