W
William J. Burlingham
Researcher at University of Wisconsin-Madison
Publications - 183
Citations - 7639
William J. Burlingham is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Transplantation & Antigen. The author has an hindex of 41, co-authored 179 publications receiving 6998 citations. Previous affiliations of William J. Burlingham include Oregon Health & Science University.
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Journal ArticleDOI
An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells
Joshua D. Mezrich,John H. Fechner,Xiaoji Zhang,Brian P. Johnson,William J. Burlingham,Christopher A. Bradfield +5 more
TL;DR: It is demonstrated that kynurenine, the first breakdown product in the IDO-dependent tryptophan degradation pathway, activates the aryl hydrocarbon receptor and this activation leads to AHR-dependent Treg generation, which shed light on the relationship of IDO to the generation of Tregs.
Journal ArticleDOI
Identification of a B cell signature associated with renal transplant tolerance in humans
Kenneth A. Newell,Adam Asare,Allan D. Kirk,Trang D. Gisler,Kasia Bourcier,Manikkam Suthanthiran,William J. Burlingham,William H. Marks,Ignacio Sanz,Robert I. Lechler,Maria P. Hernandez-Fuentes,Laurence A. Turka,Laurence A. Turka,Vicki Seyfert-Margolis +13 more
TL;DR: Results point to a critical role for B cells in regulating alloimmunity and provide a candidate set of genes for wider-scale screening of renal transplant recipients.
Journal ArticleDOI
IL-17–dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants
William J. Burlingham,Robert B. Love,Robert B. Love,Ewa Jankowska-Gan,Lynn D. Haynes,Qingyong Xu,Joseph L. Bobadilla,Keith C. Meyer,Mary S. Hayney,Rudolf K. Braun,Rudolf K. Braun,Daniel S. Greenspan,Bagavathi Gopalakrishnan,Junchao Cai,David D. Brand,Shigetoshi Yoshida,Oscar W. Cummings,David S. Wilkes +17 more
TL;DR: While alloimmunities initiates lung transplant rejection, de novo autoimmunity mediated by col(V)-specific Th17 cells and monocyte/macrophage accessory cells ultimately causes progressive airway obliteration.
Journal ArticleDOI
Human allograft acceptance is associated with immune regulation
Anne M. VanBuskirk,William J. Burlingham,Ewa Jankowska-Gan,T. Chin,S Kusaka,F Geissler,Ronald P. Pelletier,Charles G. Orosz +7 more
TL;DR: It is demonstrated that allograft acceptance in humans is associated with an immune regulation pattern, which may be useful in the diagnosis and/or monitoring of transplant patients for allografted acceptance.
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A New Model of Epstein-Barr Virus Infection Reveals an Important Role for Early Lytic Viral Protein Expression in the Development of Lymphomas
Shidong Ma,Subramanya Hegde,Ken H. Young,Ruth Sullivan,Deepika Rajesh,Ying Zhou,Ewa Jankowska-Gan,William J. Burlingham,Xiaoping Sun,Margaret L. Gulley,Weihua Tang,Jenny E. Gumperz,Shannon C. Kenney +12 more
TL;DR: An important role for lytic EBV infection in the development of B cell lymphomas is pointed to in the context of an active host immune response, suggesting that immune pressure contributed to the outcome of the infection.