D
David D. Brand
Researcher at Veterans Health Administration
Publications - 111
Citations - 7839
David D. Brand is an academic researcher from Veterans Health Administration. The author has contributed to research in topics: Arthritis & T cell. The author has an hindex of 43, co-authored 105 publications receiving 6803 citations. Previous affiliations of David D. Brand include United States Department of Veterans Affairs & University of Tennessee Health Science Center.
Papers
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Journal ArticleDOI
Collagen-induced arthritis
David D. Brand,David D. Brand,Kary A. Latham,Kary A. Latham,Edward F. Rosloniec,Edward F. Rosloniec +5 more
TL;DR: This protocol describes the steps necessary for acquisition, handling and preparation of CII, as well as selection of mouse strains, proper immunization technique and evaluation of the arthritis incidence and severity in the collagen-induced arthritis mouse model.
Journal ArticleDOI
Collagen-induced arthritis.
TL;DR: Protocols for CIA are described in this unit for both the mouse model and the rat model and support protocols are provided for assessing the severity of inflammation following CIA and for measuring B and T cell responses to CII.
Journal ArticleDOI
IL-17–dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants
William J. Burlingham,Robert B. Love,Robert B. Love,Ewa Jankowska-Gan,Lynn D. Haynes,Qingyong Xu,Joseph L. Bobadilla,Keith C. Meyer,Mary S. Hayney,Rudolf K. Braun,Rudolf K. Braun,Daniel S. Greenspan,Bagavathi Gopalakrishnan,Junchao Cai,David D. Brand,Shigetoshi Yoshida,Oscar W. Cummings,David S. Wilkes +17 more
TL;DR: While alloimmunities initiates lung transplant rejection, de novo autoimmunity mediated by col(V)-specific Th17 cells and monocyte/macrophage accessory cells ultimately causes progressive airway obliteration.
Journal ArticleDOI
Role of Vitamin A in the Immune System
TL;DR: To better understand the relationship between nutrition and the immune system, the authors review recent literature about VitA in immunity research and briefly introduce the clinical application of VitA as a therapeutic effect in the treatment of several infectious diseases.
Journal ArticleDOI
Cross-linking electrospun type II collagen tissue engineering scaffolds with carbodiimide in ethanol.
TL;DR: The hypothesis that the use of EDC in a nonaqueous solution will cross-link electrospun type II collagen fibrous matrices in a comparable manner to typical glutaraldehyde fixation protocols is tested.