William Jarra

TL;DR: This poster presents a probabilistic procedure to quantify the numbers of Gram-positive and Gram-negative parasites found in the blood of Malaria patients infected with E.coli.

TL;DR: Genus- and species-specific sequences are present within the small subunit ribosomal RNA genes of the four human malaria parasites that have proven to be more sensitive and accurate than by routine diagnostic microscopy.

TL;DR: Although a high degree of diversity characterized these isolates, the overall population structure of the parasites associated with patent malaria infections was observed to remain relatively stable over time and two interesting exceptions to the random distribution were observed.

TL;DR: A polymerase chain reaction (PCR)-based assay is described which provides a sensitive, reproducible and practical method by which parasite populations within species can be characterized and the applicability of this type of genotyping to epidemiology is discussed.

TL;DR: Vector transmission of Plasmodium regulates gene expression of probable variant antigens in the erythrocytic cycle, modifies the elicited mammalian immune response, and thus regulates parasite virulence, placing the mosquito at the centre of efforts to dissect mechanisms of protective immunity to malaria for the development of an effective vaccine.