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William Michael Dunne
Researcher at Washington University in St. Louis
Publications - 19
Citations - 840
William Michael Dunne is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Enterococcus faecium & Enterococcus faecalis. The author has an hindex of 14, co-authored 19 publications receiving 798 citations.
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Journal ArticleDOI
Impact of Clinical Symptoms on Interpretation of Diagnostic Assays for Clostridium difficile Infections
Erik R. Dubberke,Zhuolin Han,Linda D. Bobo,Tiffany Hink,Brenda Lawrence,Susan Copper,Joan Hoppe-Bauer,Carey-Ann D. Burnham,William Michael Dunne +8 more
TL;DR: In this paper, the authors measured how including patient presentation with the C. difficile assay result impacted assay performance to diagnose CDI and found that clinical presentation is important when interpreting C.difficile diagnostic assays.
Journal ArticleDOI
Mupirocin resistance in patients colonized with methicillin-resistant Staphylococcus aureus in a surgical intensive care unit.
Jeffrey C. Jones,Theodore J. Rogers,Peter Brookmeyer,William Michael Dunne,Gregory A. Storch,Craig M. Coopersmith,Victoria J. Fraser,David K. Warren +7 more
TL;DR: A high rate of mupirocin resistance in MRSA isolates from SICU patients is documented, despite low levels of in-hospital m upirocin use.
Journal ArticleDOI
Pneumonia after cecal ligation and puncture: a clinically relevant "two-hit" model of sepsis.
Jared T. Muenzer,Christopher G. Davis,Benjamin S. Dunne,Jacqueline Unsinger,William Michael Dunne,Richard S. Hotchkiss +5 more
TL;DR: Double injury, that is, cecal ligation and puncture followed by pneumonia, provides a useful tool in the study of sepsis, creating a prolonged period of infection as opposed to CLP alone.
Journal ArticleDOI
Detection of KPC-2 in a Clinical Isolate of Proteus mirabilis and First Reported Description of Carbapenemase Resistance Caused by a KPC β-Lactamase in P. mirabilis
TL;DR: An isolate of Proteus mirabilis recovered from blood cultures of a diabetic patient was shown to be resistant to imipenem, meropenem, and ertapenems by disk diffusion susceptibility testing, believed to be the first report of carbapenem resistance in P. mirabilIS caused by the acquisition of blaKPC.
Journal ArticleDOI
Epithelial apoptosis in mechanistically distinct methods of injury in the murine small intestine
Dinesh Vyas,Charles M. Robertson,Paul E. Stromberg,James Martin,William Michael Dunne,C.W. Houchen,Terrence A. Barrett,Alfred Ayala,Mario Perl,Timothy G. Buchman,Craig M. Coopersmith +10 more
TL;DR: ISOL correlates to other quantification methods of detecting gut epithelial apoptosis more than any other method studied and compares favorably to other commonly accepted techniques of quantifying apoptosis in a large intestinal cross sectional by balancing sensitivity and specificity across a range of times and levels of death.