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William Y.S. Wang
Researcher at University of Queensland
Publications - 77
Citations - 6187
William Y.S. Wang is an academic researcher from University of Queensland. The author has contributed to research in topics: Essential hypertension & Single-nucleotide polymorphism. The author has an hindex of 26, co-authored 70 publications receiving 5862 citations. Previous affiliations of William Y.S. Wang include University of Sydney & University of Leicester.
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Journal ArticleDOI
Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack
Stephen MacMahon,Bruce Neal,Christophe Tzourio,Anthony Rodgers,Mark Woodward,J. Cutler,Craig S. Anderson,John Chalmers,T. Ohkubo,M. G. Bouser,Stephen M. Davis,Geoffrey A. Donnan,L. Hansson,Stephen B. Harrap,K. R. Lees,L. Liu,G. Mancia,T. Omae,J. Reid,R. Sega,A. Terent,C. Warlow,N. Anderson,C. Bladin,B.C. Chambers,G. Gordon,N. Sharpe,Rory Collins,Peter Sandercock,John Simes,P. Sleight,A. Brnabic,S. Colman,L. Francis,A. Lee,L. Gong,M.-G. Bousser,T. Yamaguchi,F. William,Q. Deng,D. X. Hu,William Y.S. Wang,A. L. Wu,L. Y. Ma,Z. Y. Tao,V. Biousse,Karine Berthet,L. Ben Slamia,C. Le Denmat,S. Crespi,G. Foglia,C. Fujimoto,S. Matsumura,K. Marttala,M. Pettersson,M. Safwenberg,J. Fenton,Y. McIlvenna,R. Currie,H. Bartram,J. Briad,A. Clague,Y. Cleverly,M. Cosson,A. Culpan,D. Douglas,S. Flett,B. Gray,T. Holloway,A. Milne,R. Prasad,Y. Ratnasabapathy,A. Santos,M. Wills,T. Agnew,Neil Chapman,N. Lewis,B. Mullane +77 more
TL;DR: This blood-pressure-lowering regimen reduced the risk of stroke among both hypertensive and non-hypertensive individuals with a history of stroke or transient ischaemic attack, irrespective of their blood pressure.
Journal ArticleDOI
Genome-wide association studies: theoretical and practical concerns
TL;DR: The main factors — including models of the allelic architecture of common diseases, sample size, map density and sample-collection biases — that need to be taken into account in order to optimize the cost efficiency of identifying genuine disease-susceptibility loci are outlined.
Journal ArticleDOI
Parameters for reliable results in genetic association studies in common disease.
Ingrid Dahlman,Iain A. Eaves,Roman Kosoy,V. Anne Morrison,Joanne M. Heward,Stephen C. L. Gough,Amit Allahabadia,Jayne A. Franklyn,Jaakko Tuomilehto,Eva Tuomilehto-Wolf,Francesco Cucca,Cristian Guja,Constantin Ionescu-Tirgoviste,Helen Stevens,Philippa Carr,Sarah Nutland,Patricia McKinney,Julian P.H. Shield,William Y.S. Wang,Heather J. Cordell,Neil Walker,John A. Todd,Patrick Concannon +22 more
TL;DR: Using 2,873 families, a recently published association of the interleukin 12B gene in 422 type I diabetic families was unable to confirm, emphasizing the need for large datasets, small P values and independent replication if results are to be reliable.
Journal ArticleDOI
Association of angiotensin II type 1 receptor gene polymorphism with essential hypertension.
TL;DR: The present results implicate the AT1R gene, or a locus in linkage disequilibrium with the variant tested, in the causation of essential HT.
Journal ArticleDOI
Cardiac Amyloid Imaging with 18F-Florbetaben PET: A Pilot Study
W. Phillip Law,William Y.S. Wang,William Y.S. Wang,Peter T. Moore,Peter Mollee,Peter Mollee,Arnold C.T. Ng,Arnold C.T. Ng +7 more
TL;DR: 18F-florbetaben PET imaging can accurately identify and differentiate between cardiac amyloidosis and hypertensive heart disease and Percentage myocardial 18F-for Betaben retention was an independent determinant of myocardia dysfunction in cardiac ameloidosis.