W
Williams Balogun
Researcher at University of Ibadan
Publications - 26
Citations - 476
Williams Balogun is an academic researcher from University of Ibadan. The author has contributed to research in topics: Diabetes mellitus & Type 2 diabetes. The author has an hindex of 13, co-authored 25 publications receiving 375 citations. Previous affiliations of Williams Balogun include University College Hospital, Ibadan & Ladoke Akintola University of Technology.
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Journal ArticleDOI
Evaluation of Genome Wide Association Study Associated Type 2 Diabetes Susceptibility Loci in Sub Saharan Africans.
Adebowale Adeyemo,Fasil Tekola-Ayele,Ayo P. Doumatey,Amy R. Bentley,Guanjie Chen,Hanxia Huang,Jie Zhou,Daniel Shriner,Olufemi Fasanmade,Godfrey Okafor,Benjamin A. Eghan,Kofi Agyenim-Boateng,Jokotade Adeleye,Williams Balogun,Abdel G. Elkahloun,Settara C. Chandrasekharappa,Samuel Owusu,Albert G.B. Amoah,Joseph Acheampong,Thomas Johnson,Johnnie Oli,Clement Adebamowo,Francis S. Collins,Georgia M. Dunston,Charles N. Rotimi +24 more
TL;DR: The findings indicate that the genetic architecture of T2D in SSA is characterized by several risk loci shared with non-African ancestral populations and that data from African populations may facilitate fine mapping ofrisk loci.
Journal ArticleDOI
Type 2 diabetes complications and comorbidity in Sub-Saharan Africans
Kenneth Ekoru,Ayo P. Doumatey,Amy R. Bentley,Guanjie Chen,Jie Zhou,Daniel Shriner,Olufemi Fasanmade,Godfrey Okafor,Benjamin A. Eghan,Kofi Agyenim-Boateng,Jokotade Adeleye,Williams Balogun,Albert G.B. Amoah,Joseph Acheampong,Thomas Johnson,Johnnie Oli,Clement Adebamowo,Francis S. Collins,Georgia M. Dunston,Adebowale Adeyemo,Charles N. Rotimi +20 more
TL;DR: The burden of diabetes complications and comorbidity is substantial in SSA highlighting the urgent need for innovative public health strategies that prioritise promotion of healthy lifestyles for prevention and early detection of T2D.
Journal ArticleDOI
C-reactive protein (CRP) promoter polymorphisms influence circulating CRP levels in a genome-wide association study of African Americans
Ayo P. Doumatey,Guanjie Chen,Fasil Tekola Ayele,Jie Zhou,Michael R. Erdos,Daniel Shriner,Hanxia Huang,Jokotade Adeleye,Williams Balogun,Olufemi Fasanmade,Thomas Johnson,Johnnie Oli,Godfrey Okafor,Albert G.B. Amoah,Benjamin A. Eghan,Kofi Agyenim-Boateng,Joseph Acheampong,Clement Adebamowo,Clement Adebamowo,Norman P. Gerry,Michael F. Christman,Adebowale Adeyemo,Charles N. Rotimi +22 more
TL;DR: CRP signals previously identified in EA samples were transferable to AAs, and the team was able to fine-map this signal, reducing the region of interest from the 25 kb of LD around the locus in the HapMap CEU sample to only 8 kb in the AA sample.
Journal ArticleDOI
Genome-wide associated loci influencing interleukin (IL)-10, IL-1Ra, and IL-6 levels in African Americans
Fasil Tekola Ayele,Ayo P. Doumatey,Hanxia Huang,Jie Zhou,Bashira A. Charles,Michael R. Erdos,Jokotade Adeleye,Williams Balogun,Olufemi Fasanmade,Thomas Johnson,Johnnie Oli,Godfrey Okafor,Albert G.B. Amoah,Benjamin A. Eghan,Kofi Agyenim-Boateng,Joseph Acheampong,Clement Adebamowo,Alan Herbert,Norman P. Gerry,Michael F. Christman,Guanjie Chen,Daniel Shriner,Adebowale Adeyemo,Charles N. Rotimi +23 more
TL;DR: A genome-wide association study of IL-10, IL-1Ra, and IL-6 levels in 707 non-diabetic African Americans using 5,396,780 imputed and directly genotyped single nucleotide polymorphisms (SNPs) with adjustment for gender, age, and body mass index to provide useful insights into mechanisms of immune response and pathogenesis of diseases.
Journal ArticleDOI
Maternal malaria status and metabolic profiles in pregnancy and in cord blood: relationships with birth size in Nigerian infants.
O Ayoola,O Ayoola,Andrew Whatmore,Williams Balogun,Olatokunbo O Jarrett,John Kennedy Cruickshank,Peter E. Clayton +6 more
TL;DR: In the setting of endemic malaria, maternal total cholesterol during pregnancy and cord blood insulin and IGF-I levels are potential biomarkers of foetal growth and birth size.