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Willy Min Jou
Researcher at Laboratory of Molecular Biology
Publications - 34
Citations - 3314
Willy Min Jou is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 26, co-authored 34 publications receiving 3234 citations. Previous affiliations of Willy Min Jou include Ghent University.
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Journal ArticleDOI
A universal influenza A vaccine based on the extracellular domain of the M2 protein.
TL;DR: The enhanced immunogenicity of the M2 extracellular domain exposed on HBc particles allows broad-spectrum, long-lasting protection against influenza A infections.
Journal ArticleDOI
Universal influenza A vaccine: optimization of M2-based constructs.
Marina De Filette,Willy Min Jou,Ashley Birkett,Katie Lyons,Brian Schultz,Anne Tonkyro,Stephanie Resch,Walter Fiers +7 more
TL;DR: Although HBc is highly immunogenic, the optimized M2e-HBc vaccine induced an anti-M2e antibody titer even higher than that of anti- HBc, which resulted in strong immunogenicity and full protection after either intraperitoneal or intranasal administration.
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Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75.
Martine Verhoeyen,Rongxiang Fang,Willy Min Jou,René Devos,Danny Huylebroeck,Eric Saman,Walter Fiers +6 more
TL;DR: A DNA copy of the gene coding for the influenza A/Aichi/2/68 haemagglutinin protein was cloned in the plasmid pBR322 and the complete nucleotide sequence determined and documents further at the molecular level the two independent modes of antigenic variation of the virus—drift and shift.
Journal ArticleDOI
Complete structure of the hemagglutinin gene from the human influenza A/Victoria/3/75 (H3N2) strain as determined from cloned DNA
Willy Min Jou,Martine Verhoeyen,René Devos,Eric Saman,Rongxiang Fang,Danny Huylebroeck,Walter Fiers,Geoffrey Threlfall,Christine Barber,Norman Henry Carey,Spencer Emtage +10 more
TL;DR: The complete sequence of a hemagglutinin (HA) gene of a recent human influenza A strain, A/Victoria/3/75, is 1768 nucleotides long and contains the information for 567 amino acids as mentioned in this paper.
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Complete structure of A/duck/Ukraine/63 influenza hemagglutinin gene: Animal virus as progenitor of human H3 Hong Kong 1968 influenza hemagglutinin
TL;DR: It is concluded that the duck/Ukraine/63 hemagglutinin sequence fully corroborates its previous identification by immunological and other methods as belonging to the H3 subtype and provides support at the molecular level for the general idea that the wide variety of influenza viruses known to be present in animals can serve as a gene reservoir for human influenza A viruses.