W
Wolfgang Pfleiderer
Researcher at University of Konstanz
Publications - 735
Citations - 9907
Wolfgang Pfleiderer is an academic researcher from University of Konstanz. The author has contributed to research in topics: Nucleotide & Pteridine. The author has an hindex of 43, co-authored 735 publications receiving 9765 citations. Previous affiliations of Wolfgang Pfleiderer include Duke University & Novartis.
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Pteridine nucleotide analogs as fluorescent dna probes
TL;DR: In this paper, a pteridine nucleotide which is highly fluorescent under physiological conditions and which may be used in the chemical synthesis of fluorescent oligonucleotides was proposed.
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Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present.
Ernst R. Werner,Gabriele Werner-Felmayer,Dietmar Fuchs,Arno Hausen,Gilbert Reibnegger,J J Yim,Wolfgang Pfleiderer,H. Wachter +7 more
TL;DR: Upon interferon-gamma treatment, GTP-cyclohydrolase I activity is increased 7- to 40-fold, whereas 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase activities, which are constitutively present in all four investigated cells, remain unchanged.
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The p-nitrophenylethyl (NPE) group: A versatile new blocking group for phosphate and aglycone protection in nucleosides and nucleotides
Frank Himmelsbach,Bernd S. Schulz,Thomas Trichtinger,Ramamurthy Charubala,Wolfgang Pfleiderer +4 more
TL;DR: In this paper, the synthesis of new monomer building blocks for oligonucleotide synthesis via the phosphotriester approach containing the p -nitrophenylethyl group for phosphate and aglycone protection are described.
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Photolabile protecting groups for nucleosides: Synthesis and photodeprotection rates
A. Hasan,Klaus-Peter Stengele,Heiner Giegrich,Paul Cornwell,Kenneth R. Isham,Richard A. Sachleben,Wolfgang Pfleiderer,Robert S. Foote +7 more
TL;DR: In this paper, a series of 5'-O-protected thymidine derivatives irradiated at 365 nm under identical conditions were tested for photolabile protection of nucleoside 5'-hydroxyls.
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Structure of a Novel Oligosaccharide-Mycosporine-Amino Acid Ultraviolet A/B Sunscreen Pigment from the Terrestrial Cyanobacterium Nostoc commune
TL;DR: Water-soluble UV-A/B-absorbing pigments secreted by cells of the cosmopolitan terrestrial cyanobacterium Nostoc commune are the first mycosporines to be described covalently linked to oligosaccharides.