Wuraola A. Shokunbi

TL;DR: Worries over psychosocial consequences of SCD, seem to add considerably to the burden of illness, and clinicians will offer better care to patients if they routinely enquire into some of these issues and offer health education and counselling in a group setting.

TL;DR: HPCidin levels are lower in children with SMA or CM than in those with milder outcome (UM), and a role for hepcidin in anti-inflammatory processes in childhood malaria is proposed.

TL;DR: In this article, the authors used an outbred-rat model where increasing parasite removal in the spleen escalated uninfected-erythrocyte removal, and showed that CD8+ T cell-dependent parasite clearance may predispose individuals to infection and SMA.

TL;DR: The presence of generalized vascular inflammation, vascular wall modulations, activation of endothelium and unbalanced glucose metabolism in severe malaria suggests the increased levels of specific muscle proteins in plasma implicate potential muscle damage and microvasculature lesions during the course of cerebral malaria.

TL;DR: The psychosocial burden of SCD can be significantly reduced by controlling the frequency and duration of crises, as well as providing adequate information and socioeconomic support to families.