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Xi Chen
Researcher at University of California, Davis
Publications - 629
Citations - 28889
Xi Chen is an academic researcher from University of California, Davis. The author has contributed to research in topics: Sialic acid & Medicine. The author has an hindex of 71, co-authored 548 publications receiving 22541 citations. Previous affiliations of Xi Chen include University of California, Riverside & Cleveland Clinic.
Papers
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Journal ArticleDOI
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
Brian D. Lehmann,Joshua A. Bauer,Xi Chen,Melinda E. Sanders,A. Bapsi Chakravarthy,Yu Shyr,Jennifer A. Pietenpol +6 more
TL;DR: Gen expression profiles from 21 breast cancer data sets and identified 587 TNBC cases may be useful in biomarker selection, drug discovery, and clinical trial design that will enable alignment of TNBC patients to appropriate targeted therapies.
Journal ArticleDOI
Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection
Brian D. Lehmann,Bojana Jovanovic,Xi Chen,Monica V. Estrada,Kimberly N. Johnson,Yu Shyr,Harold L. Moses,Melinda E. Sanders,Jennifer A. Pietenpol +8 more
TL;DR: Pre-clinical data is provided that could inform clinical trials designed to test the hypothesis that improved outcomes can be achieved for TNBC patients, if selection and combination of existing chemotherapies is directed by knowledge of molecular TNBC subtypes.
Journal ArticleDOI
Random forests for genomic data analysis.
TL;DR: This article systematically review the applications and recent progresses of RF for genomic data, including prediction and classification, variable selection, pathway analysis, genetic association and epistasis detection, and unsupervised learning.
Journal ArticleDOI
Cu-Catalyzed Click Reaction in Carbohydrate Chemistry
TL;DR: This review highlights the successful advancement of Cu(I)-catalyzed click chemistry in glycoscience and its applications as well as future scope in different streams of applied sciences.
Journal ArticleDOI
Advances in the Biology and Chemistry of Sialic Acids
Xi Chen,Ajit Varki +1 more
TL;DR: A large library of sialoside standards and derivatives in amounts sufficient for structure-activity relationship studies are provided and sialoglycan microarrays provide an efficient platform for quick identification of preferred ligands for sialic acid-binding proteins.