X
Xi Chen
Researcher at University of California, Davis
Publications - 629
Citations - 28889
Xi Chen is an academic researcher from University of California, Davis. The author has contributed to research in topics: Sialic acid & Medicine. The author has an hindex of 71, co-authored 548 publications receiving 22541 citations. Previous affiliations of Xi Chen include University of California, Riverside & Cleveland Clinic.
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Journal ArticleDOI
Long-Term IgG Response to Porcine Neu5Gc Antigens without Transmission of PERV in Burn Patients Treated with Porcine Skin Xenografts
Linda Scobie,Vered Padler-Karavani,Stéphanie Le Bas-Bernardet,Claire Crossan,Josef Blaha,Magda Matouskova,Ralph D. Hector,Emanuele Cozzi,Bernard Vanhove,Béatrice Charreau,Gilles Blancho,Ludovic Bourdais,Mariachiara Tallacchini,Juan M. Ribes,Hai Yu,Xi Chen,Jitka Kracikova,Broz L,Jiri Hejnar,Pavel Vesely,Pavel Vesely,Yasuhiro Takeuchi,Ajit Varki,Jean-Paul Soulillou +23 more
TL;DR: Blood of burn patients who had received living pig-skin dressings for up to 8 wk was analyzed for the presence of PERV as well as for the level and nature of their long term immune response against pig Ags, suggesting that anti-Neu5Gc Abs represent a barrier for long-term acceptance of porcine xenografts.
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Predicting normal glenoid version from the pathologic scapula: a comparison of 4 methods in 2- and 3-dimensional models
TL;DR: The ability to take 3-D CT scan-based measurements in a scapula with pathologic glenoids retroversion and predict the native (nonpathologic) glenoid version in the contralateral shoulder by using linear regression equations or a computer generated vault model is demonstrated.
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Recent progress in chemical and chemoenzymatic synthesis of carbohydrates.
TL;DR: This review highlights recent progress in chemical and chemoenzymatic synthesis of carbohydrates with a particular focus on the methods developed for the synthesis of oligosaccharide, polysaccharides, glycolipids, and glycosylated natural products.
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A Sialyltransferase Mutant with Decreased Donor Hydrolysis and Reduced Sialidase Activities for Directly Sialylating Lewisx
Go Sugiarto,Kam Lau,Jingyao Qu,Yanhong Li,Sunghyuk Lim,Shengmao Mu,James B. Ames,Andrew J. Fisher,Xi Chen +8 more
TL;DR: It is shown here that the sugar nucleotide donor hydrolysis activity of glycosyltransferases contributes significantly to the low yield ofglycosylation when a poor acceptor substrate is used, and a novel strategy to improve gly cosyltransferase substrate promiscuity by decreasing its donor hydroleysis activity is provided.
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Cross-comparison of protein recognition of sialic acid diversity on two novel sialoglycan microarrays
Vered Padler-Karavani,Xuezheng Song,Hai Yu,Nancy Hurtado-Ziola,Shengshu Huang,Saddam Muthana,Harshal A. Chokhawala,Jiansong Cheng,Andrea Verhagen,Martijn A. Langereis,Ralf Kleene,Melitta Schachner,Raoul J. de Groot,Yi Lasanajak,Haruo Matsuda,Richard Schwab,Xi Chen,David F. Smith,Richard D. Cummings,Ajit Varki +19 more
TL;DR: Two arrays that together represent the marked diversity of sialic acid modifications, linkages, and underlying glycans in nature are compared, showing that different presentations in different formats provide useful and complementary interpretations of glycan-binding protein specificity.