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Xianchan Li

Researcher at University of Gothenburg

Publications -  50
Citations -  1987

Xianchan Li is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Exocytosis & Vesicle. The author has an hindex of 22, co-authored 46 publications receiving 1656 citations. Previous affiliations of Xianchan Li include Minzu University of China & Chalmers University of Technology.

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Quantitative Measurement of Transmitters in Individual Vesicles in the Cytoplasm of Single Cells with Nanotip Electrodes

TL;DR: The results demonstrate that only a fraction of the quantal neurotransmitter content is released during exocytosis, thus supporting the intriguing hypothesis that the vesicle does not open all the way during the normal exocyTosis process, thus resulting in incomplete expulsion of thevesicular contents.
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Aptamer-Based Electrochemical Sensors with Aptamer−Complementary DNA Oligonucleotides as Probe

TL;DR: A facile and general strategy for the development of aptamer-based electrochemical sensors with a high specificity toward the targets and a ready regeneration feature is described, and the aptasensors demonstrated here with the cDNA as the probe are readily regenerated and show good responses toward the target sensing.
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Measuring synaptic vesicles using cellular electrochemistry and nanoscale molecular imaging

TL;DR: Making use of fluorescent or isotopically labelled probes enables super-resolution optical and mass spectrometric imaging of molecular composition and activity of single vesicles, which has proved advantageous in understanding the relationship between vesicle structure and function.
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Transferrin serves as a mediator to deliver organometallic ruthenium(II) anticancer complexes into cells.

TL;DR: HTf can serve as a mediator for the targeting delivery of Ru(arene) anticancer complexes while deactivating cisplatin, and the binding to holo-hTf well preserved the bioavailability of the ruthenium complexes.
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A facile electrochemical method for simultaneous and on-line measurements of glucose and lactate in brain microdialysate with prussian blue as the electrocatalyst for reduction of hydrogen peroxide.

TL;DR: A facile electrochemical method for simultaneous and selective on-line measurements of glucose and lactate in the brain of freely moving rats through integration of selective electrochemical detection with in vivo microdialysis is demonstrated.