Journal ArticleDOI
PEGylated dendrimer-entrapped gold nanoparticles for in vivo blood pool and tumor imaging by computed tomography
Chen Peng,Linfeng Zheng,Qian Chen,Mingwu Shen,Rui Guo,Han Wang,Xueyan Cao,Guixiang Zhang,Xiangyang Shi,Xiangyang Shi +9 more
TLDR
The designed PEGylated Au DENPs can be used as a promising contrast agent with enhanced biocompatibility for CT imaging of various biological systems, especially in cancer diagnosis.About:
This article is published in Biomaterials.The article was published on 2012-02-01. It has received 363 citations till now. The article focuses on the topics: Dendrimer.read more
Citations
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Nanomaterials for theranostics: recent advances and future challenges.
Eun Kyung Lim,Eun Kyung Lim,Taekhoon Kim,Taekhoon Kim,Soonmyung Paik,Seungjoo Haam,Yong Min Huh,Kwangyeol Lee +7 more
TL;DR: Challenges Eun-Kyung Lim,†,‡,§ Taekhoon Kim, Soonmyung Paik, Seungjoo Haam, Yong-Min Huh,*,† and Kwangyeol Lee
Journal ArticleDOI
X-ray-Computed Tomography Contrast Agents
Hrvoje Lusic,Mark W. Grinstaff +1 more
TL;DR: The strong relationship between absorption and atomic number is of significant importance in clinical applications and the Z4 factor allows for contrast levels of several orders of magnitude between different tissues and types of contrast agents.
Journal ArticleDOI
State of the art in gold nanoparticle synthesis
TL;DR: In this article, general principles and recent developments in the synthesis of gold nanoparticles (AuNPs) are reviewed and a review of seed-growth methods have allowed a precise control of AuNP sizes in a broad range and multiple shapes.
Journal ArticleDOI
Multifunctional Gold Nanoparticles for Diagnosis and Therapy of Disease
TL;DR: This review covers basic principles and recent findings in gold nanoparticle applications for imaging, therapy and diagnostics, with a focus on reports of multifunctional AuNPs.
Journal ArticleDOI
Nano‐Sized CT Contrast Agents
TL;DR: Nano‐sized iodinated CT contrast agents have been developed that can increase the circulation time and decrease the adverse effects and nanoparticles based on heavy atoms such as gold, lanthanides, and tantalum are used as more efficientCT contrast agents.
References
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Journal ArticleDOI
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review.
TL;DR: The basic characteristics of the EPR effect, particularly the factors involved, are described, as well as its modulation for improving delivery of macromolecular drugs to the tumor.
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Gold Nanoparticles Are Taken Up by Human Cells but Do Not Cause Acute Cytotoxicity
Journal ArticleDOI
Gold nanoparticles: a new X-ray contrast agent
TL;DR: Gold nanoparticles can be used as X-ray contrast agents with properties that overcome some significant limitations of iodine-based agents, and this report is the first demonstration that gold nanoparticles may overcome these limitations.
Journal ArticleDOI
Polymeric drugs for efficient tumor-targeted drug delivery based on EPR-effect
TL;DR: The EPR-effect appears as a universal phenomenon in solid tumors which warrants the development of other polymeric drugs or nanomedicine, and then advantages and problems of macromolecular drugs.
Book
Dendrimers and other dendritic polymers
TL;DR: The author reveals some unique Features of Dendrimers based upon Self--assembly and Host--Guest Properties that have attracted attention in the literature on Dendritic Polymers and their applications in Nanobiological Devices.