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Xiao-Chun Zhang
Researcher at Nanjing University of Chinese Medicine
Publications - 2
Citations - 182
Xiao-Chun Zhang is an academic researcher from Nanjing University of Chinese Medicine. The author has contributed to research in topics: Apoptosis & Strychnos nux-vomica. The author has an hindex of 2, co-authored 2 publications receiving 171 citations.
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The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism
Xu-Kun Deng,Wu Yin,Weidong Li,Fangzhou Yin,Xiaoyu Lu,Xiao-Chun Zhang,Zi-Chun Hua,Baochang Cai +7 more
TL;DR: It is indicated that the major alkaloids present in the seed of Strychnos nux-vomica are effective against HepG2 cells proliferation, among which brucine proceed HepG 2 cells death via apoptosis, probably through the participation of caspase-3 and cyclooxygenase-2.
Journal ArticleDOI
The cytotoxicity induced by brucine from the seed of Strychnos nux-vomica proceeds via apoptosis and is mediated by cyclooxygenase 2 and caspase 3 in SMMC 7221 cells.
TL;DR: It is indicated that the major alkaloids present in the seed of Strychnos nux-vomica are effective against SMMC-7721 cells proliferation, among which brucine proceeds SMMC 7721 cells death via apoptosis, probably through the participation of caspase 3 and cyclooxygenase 2.