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Xiao Zhang

Researcher at Shanghai Jiao Tong University

Publications -  42
Citations -  1628

Xiao Zhang is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Cancer & Liver cancer. The author has an hindex of 16, co-authored 42 publications receiving 887 citations. Previous affiliations of Xiao Zhang include Tongji University.

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The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis

TL;DR: It is found via in vitro cell-based and in vivo mouse model experiments that O-GlcNAcylation of YAP was required for high-glucose-induced liver tumorigenesis and is a potential therapeutic intervention point for treating liver cancer associated with high blood glucose levels and possibly diabetes.
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Ferroptosis is governed by differential regulation of transcription in liver cancer

TL;DR: Two categories of genes are identified: ferroptosis up-regulated factors (FUF) and FDF, which stimulate and suppress ferroPTosis by affecting the synthesis of GSH, and disrupting the balance between HIC1 and HNF4A might be helpful in treating liver cancer.
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The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function.

TL;DR: It is demonstrated that the m6A reader YT521-B homology domain containing 2 (YTHDC2) is frequently suppressed in lung adenocarcinoma (LUAD), and blocking this process may benefit future treatment of lung tumorigenesis.
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Effects of exercise intervention in breast cancer survivors: a meta-analysis of 33 randomized controlled trails

TL;DR: The study suggested that exercise intervention was beneficial to breast cancer survivors, and exercise should be recommended to this patient group.