Q
Qiuhui Pan
Researcher at Shanghai Jiao Tong University
Publications - 73
Citations - 4085
Qiuhui Pan is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Ubiquitin ligase & Cell. The author has an hindex of 25, co-authored 63 publications receiving 3469 citations. Previous affiliations of Qiuhui Pan include Sun Yat-sen University & Tongji University.
Papers
More filters
Journal ArticleDOI
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
Fengyan Yu,Fengyan Yu,Herui Yao,Pengcheng Zhu,Xiaoqin Zhang,Qiuhui Pan,Chang Gong,Yijun Huang,Xiaoqu Hu,Fengxi Su,Judy Lieberman,Erwei Song +11 more
TL;DR: Let-7 regulates multiple BT-IC stem cell-like properties by silencing more than one target, and miRNA expression in self-renewing and differentiated cells from breast cancer lines and in breast T-IC and non-BT-IC from 1 degrees breast cancers is compared.
Journal ArticleDOI
circRNA_104075 stimulates YAP-dependent tumorigenesis through the regulation of HNF4a and may serve as a diagnostic marker in hepatocellular carcinoma.
Xiao Zhang,Yanfeng Xu,Zijun Qian,Weisheng Zheng,Qi Wu,Yan Chen,Guoqing Zhu,Ya Liu,Zhixuan Bian,Wen Xu,Yue Zhang,Fenyong Sun,Qiuhui Pan,Jiayi Wang,Lutao Du,Yongchun Yu +15 more
TL;DR: It is determined that circ_104075 was highly expressed in HCC and its upstream and downstream regulatory mechanisms are elucidated and it has the potential to serve as a new diagnostic biomarker in H CC.
Journal ArticleDOI
The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis
Xiao Zhang,Yongxia Qiao,Qi Wu,Yan Chen,Shaowu Zou,Xiangfan Liu,Guoqing Zhu,Yinghui Zhao,Yuxin Chen,Yongchun Yu,Qiuhui Pan,Jiayi Wang,Fenyong Sun +12 more
TL;DR: It is found via in vitro cell-based and in vivo mouse model experiments that O-GlcNAcylation of YAP was required for high-glucose-induced liver tumorigenesis and is a potential therapeutic intervention point for treating liver cancer associated with high blood glucose levels and possibly diabetes.
Journal ArticleDOI
Mutual interaction between YAP and CREB promotes tumorigenesis in liver cancer
Jiayi Wang,Lifang Ma,Wenhao Weng,Yongxia Qiao,Yue Zhang,Jiangtu He,Hongmei Wang,Weifan Xiao,Lanlan Li,Qinghua Chu,Qiuhui Pan,Yongchun Yu,Fenyong Sun +12 more
TL;DR: It is found that YAP‐CREB interaction is critical for liver cancer cell survival and maintenance of transformative phenotypes, both in vitro and in vivo, and there is a novel positive autoregulatory feedback loop underlying the interaction between YAP and CREB.
Journal ArticleDOI
Ferroptosis is governed by differential regulation of transcription in liver cancer
Xiao Zhang,Lutao Du,Yongxia Qiao,Xiaobai Zhang,Weisheng Zheng,Qi Wu,Yan Chen,Guoqing Zhu,Ya Liu,Zhixuan Bian,Susu Guo,Yueyue Yang,Lifang Ma,Yongchun Yu,Qiuhui Pan,Fenyong Sun,Jiayi Wang +16 more
TL;DR: Two categories of genes are identified: ferroptosis up-regulated factors (FUF) and FDF, which stimulate and suppress ferroPTosis by affecting the synthesis of GSH, and disrupting the balance between HIC1 and HNF4A might be helpful in treating liver cancer.