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Xiaobo Sun
Researcher at Sun Yat-sen University
Publications - 52
Citations - 719
Xiaobo Sun is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Encephalitis & Neuromyelitis optica. The author has an hindex of 12, co-authored 45 publications receiving 438 citations.
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Journal ArticleDOI
Gut dysbiosis and lack of short chain fatty acids in a Chinese cohort of patients with multiple sclerosis
Qin Zeng,Junli Gong,Xiyuan Liu,Chen Chen,Xiaobo Sun,Huijuan Li,Yifan Zhou,Chunping Cui,Yuge Wang,Yu Yang,Aimin Wu,Yaqing Shu,Xueqiang Hu,Zhengqi Lu,Song Guo Zheng,Wei Qiu,Yongjun Lu +16 more
TL;DR: Gut dysbiosis and a lack of SCFAs exist in Chinese MS patients, which might be related to an aberrant immune response of MS; this relationship may have a diagnostic and therapeutic value for patients with MS.
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Post-stroke DHA Treatment Protects Against Acute Ischemic Brain Injury by Skewing Macrophage Polarity Toward the M2 Phenotype
TL;DR: It is demonstrated that post-stroke DHA injection efficiently reduced brain infarct and ameliorated neurological deficits 3 days after tMCAO and DHA enhanced macrophage phenotypic shift toward an anti-inflammatory phenotype to reduced central and peripheral inflammation after stroke.
Journal ArticleDOI
HLA class II allele DRB1*16:02 is associated with anti-NMDAR encephalitis.
Yaqing Shu,Wei Qiu,Junfeng Zheng,Xiaobo Sun,Junping Yin,Xiaoli Yang,Xiaoyang Yue,Chen Chen,Zhihui Deng,Shasha Li,Yu Yang,Fuhua Peng,Zhengqi Lu,Xueqiang Hu,Frank Petersen,Xinhua Yu +15 more
TL;DR: This study for the first time demonstrates an association between specific HLA class II alleles and anti-NMDAR encephalitis, providing novel insights into the pathomechanism of the disease.
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Different features between pediatric-onset and adult-onset patients who are seropositive for MOG-IgG: A multicenter study in South China
Lu Chen,Chen Chen,Xiaonan Zhong,Xiaobo Sun,Haixia Zhu,Xiaojing Li,Hui Yang,Yaqing Shu,Yanyu Chang,Xueqiang Hu,Zhengqi Lu,Lisheng Peng,Wei Qiu +12 more
TL;DR: Distinctive features are present between pediatric-ONSet and adult-onset patients with MOG-IgG, and the different underlying pathogenesis of MOG antibody at different ages is determined.
Journal ArticleDOI
Lack of short-chain fatty acids and overgrowth of opportunistic pathogens define dysbiosis of neuromyelitis optica spectrum disorders: A Chinese pilot study.
Junli Gong,Wei Qiu,Qin Zeng,Xiyuan Liu,Xiaobo Sun,Huijuan Li,Yu Yang,Aimin Wu,Jian Bao,Yuge Wang,Yaqing Shu,Xueqiang Hu,Joseph A. Bellanti,Song Guo Zheng,Yongjun Lu,Zhengqi Lu +15 more
TL;DR: The fecal organismal structures and SCFAs level of patients with NMOSD were distinctive from healthy individuals, which could be critical events driving the aberrant immune response responsible for the pathogenesis of these disorders but could also provide suggestions for disease therapy.