Journal ArticleDOI
Different features between pediatric-onset and adult-onset patients who are seropositive for MOG-IgG: A multicenter study in South China
Lu Chen,Chen Chen,Xiaonan Zhong,Xiaobo Sun,Haixia Zhu,Xiaojing Li,Hui Yang,Yaqing Shu,Yanyu Chang,Xueqiang Hu,Zhengqi Lu,Lisheng Peng,Wei Qiu +12 more
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TLDR
Distinctive features are present between pediatric-ONSet and adult-onset patients with MOG-IgG, and the different underlying pathogenesis of MOG antibody at different ages is determined.About:
This article is published in Journal of Neuroimmunology.The article was published on 2018-08-15. It has received 42 citations till now.read more
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E.U. paediatric MOG consortium consensus: Part 1 - Classification of clinical phenotypes of paediatric myelin oligodendrocyte glycoprotein antibody-associated disorders.
Arlette L. Bruijstens,Christian Lechner,Lorraine Flet-Berliac,Kumaran Deiva,Rinze F. Neuteboom,Cheryl Hemingway,Evangeline Wassmer,Eva-Maria Wendel,Markus Breu,Aliénor de Chalus,Marco Capobianco,Giorgi Laetitia,Ming K. Lim,Ronny Wickström,Thaís Armangue +14 more
TL;DR: This review concludes with recommendations following expert consensus on serologic testing for MOG-abs in paediatric patients, the presence of which has consequences for long-term monitoring, relapse risk, treatments, and for counselling of patient and families.
Journal ArticleDOI
Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease: International MOGAD Panel proposed criteria
TL;DR: In this article , the authors proposed diagnostic criteria for MOG antibody-associated disease (MOGAD) in which the presence of MOG-IgG is a core criterion.
Journal ArticleDOI
Diagnosis of myelin oligodendrocyte glycoprotein antibody-associated disease: International MOGAD Panel proposed criteria
Brenda Banwell,Jeffrey Bennett,Romain Marignier,Ho Kim,Fabienne Brilot,Eoin P. Flanagan,Sudarshini Ramanathan,Patrick Waters,Silvia Tenembaum,Jennifer Graves,Tanuja Chitnis,Alexander U. Brandt,Cheryl Hemingway,Rinze F. Neuteboom,Lekha Pandit,Markus Reindl,Albert Saiz,Douglas Kazutoshi Sato,Kevin Rostasy,Friedemann Paul,Sean J. Pittock,Kazuo Fujihara,Jacqueline Palace +22 more
Journal ArticleDOI
E.U. paediatric MOG consortium consensus: Part 3 - Biomarkers of paediatric myelin oligodendrocyte glycoprotein antibody-associated disorders.
Arlette L. Bruijstens,Eva-Maria Wendel,Christian Lechner,Frederik Bartels,Carsten Finke,Markus Breu,Lorraine Flet-Berliac,Aliénor de Chalus,Catherine Adamsbaum,Marco Capobianco,Giorgi Laetitia,Yael Hacohen,Cheryl Hemingway,Evangeline Wassmer,Ming K. Lim,Matthias Baumann,Ronny Wickström,Thaís Armangue,Kevin Rostasy,Kumaran Deiva,Rinze F. Neuteboom +20 more
TL;DR: Four first-line therapies consisting of rituximab (RTX), azathioprine, mycophenolate mofetil or monthly IVIG have been identified and the consensus group recommends treatment escalation with RTX or IVIG, followed by combining those two, and ultimately adding maintenance oral steroids.
Journal ArticleDOI
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disorders: Toward a New Spectrum of Inflammatory Demyelinating CNS Disorders?
Di Pauli F,Thomas Berger +1 more
TL;DR: The findings regarding MOG antibodies as potential biological markers in discriminating between these different demyelinating CNS diseases are presented, and recent developments, clinical implementations, and data on immunopathogenesis of MOG antibody-associated disorders are discussed.
References
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Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria
Chris H. Polman,Stephen C. Reingold,Brenda Banwell,Michel Clanet,Jeffrey A. Cohen,Massimo Filippi,Kazuo Fujihara,Eva Havrdova,Michael Hutchinson,Ludwig Kappos,Fred D. Lublin,Xavier Montalban,Paul L. O’Connor,Magnhild Sandberg-Wollheim,Alan J. Thompson,Emmanuelle Waubant,Brian G. Weinshenker,Jerry S. Wolinsky +17 more
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International consensus diagnostic criteria for neuromyelitis optica spectrum disorders
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TL;DR: The International Panel for NMO Diagnosis (IPND) was convened to develop revised diagnostic criteria using systematic literature reviews and electronic surveys to facilitate consensus and achieved consensus on pediatric NMOSD diagnosis and the concepts of monophasicNMOSD and opticospinal MS.
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Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.
Deborah C. Rice,Stan Barone +1 more
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International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions
Lauren B. Krupp,Marc Tardieu,Maria Pia Amato,Brenda Banwell,Tanuja Chitnis,Russell C. Dale,Angelo Ghezzi,Rogier Q. Hintzen,Andrew J. Kornberg,Daniela Pohl,Kevin Rostasy,Silvia Tenembaum,Evangeline Wassmer +12 more
TL;DR: Revised criteria are proposed for pediatric acute disseminated encephalomyelitis, pediatric clinically isolated syndrome, pediatric neuromyELitis optica and pediatric MS to incorporate advances in delineating the clinical and neuroradiologic features of these disorders.
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