Xiaochun Li

TL;DR: Patients receiving the higher fresolimumab dose had a favorable systemic immune response and experienced longer median overall survival than the lower dose group, and the higher dose correlated with improved peripheral blood mononuclear cell counts and a striking boost in the CD8 central memory pool.

TL;DR: This study provides Class III evidence that for patients with MS, natalizumab EID is associated with a lower PML risk than SID.

TL;DR: Altered expression signatures of TGF-β1 signaling are identified that may be responsible for MF in Gata1(low) mice and may represent additional targets for therapeutic intervention in PMF.

TL;DR: Everolimus-carboplatin was efficacious in metastatic TNBC and dose limiting hematological toxicity was observed when AUC5/6 of carboplatin is combined with everolimus, however, carboplarin AUC 4 was well tolerated in combination with Everolimus with continuing responses.

TL;DR: The results provide initial evidence that full-term pregnancy induces long-term genomic changes in the breast, and could be used as an intermediate marker to assess potential chemopreventive interventions with hormones mimicking the effects of pregnancy for prevention of breast cancer.