X
Xiaocong Yu
Researcher at Vanderbilt University Medical Center
Publications - 5
Citations - 579
Xiaocong Yu is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Monoclonal antibody & Engineering. The author has an hindex of 2, co-authored 3 publications receiving 522 citations.
Papers
More filters
Journal ArticleDOI
Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors
Xiaocong Yu,Tshidi Tsibane,Patricia A. McGraw,Frances S. House,Christopher J. Keefer,Mark D. Hicar,Terrence M. Tumpey,Claudia Pappas,Claudia Pappas,Lucy A. Perrone,Osvaldo Martinez,James Stevens,James Stevens,Ian A. Wilson,Patricia V. Aguilar,Eric Lewin Altschuler,Christopher F. Basler,James E. Crowe +17 more
TL;DR: It is demonstrated that survivors of the 1918 influenza pandemic possess highly functional, virus-neutralizing antibodies to this uniquely virulent virus, and that humans can sustain circulating B memory cells to viruses for many decades after exposure—well into the tenth decade of life.
Journal ArticleDOI
An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies.
TL;DR: A novel electrofusion protocol for efficiently fusing Epstein-Barr virus-transformed human B cells with myeloma partners is developed and obtained human hybridomas that secrete fully human monoclonal antibodies against two major human respiratory pathogens.
Journal ArticleDOI
Corrigendum: Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors
Xiaocong Yu,Tshidi Tsibane,Patricia A. McGraw,Frances S. House,Christopher J. Keefer,Mark D. Hicar,Terrence M. Tumpey,Claudia Pappas,Lucy A. Perrone,Osvaldo Martinez,James Stevens,Ian A. Wilson,Patricia V. Aguilar,Eric L. Altschuler,Christopher F. Basler,James E. Crowe +15 more
TL;DR: This corrects the article to show that the method used to derive the H2O2 “spatially aggregating force” is a two-step process, rather than a single step, like in the previous version of this paper.
Journal ArticleDOI
Honing-in antigen-specific cells during antibody discovery: a user-friendly process to mine a deeper repertoire
Ankit Mahendra,Aftabul Haque,Ponraj Prabakaran,Brian C. Mackness,Thomas P. Fuller,Xiaohua Liu,Sagar V. Kathuria,Yui-Hsi Wang,Nilesh Amatya,Xiaocong Yu,Joern Hopke,Dietmar Hoffmann,Eva Bric-Furlong,Ningning Zhang,Hyun-Suk Cho,Ruijun Zhang,Jose Sancho,Jacqueline Saleh,Sambasiva P. Rao,Maria Wendt,Partha S. Chowdhury +20 more
TL;DR: In this paper , the authors report on the bulk purification of antigen-specific B-cells and the benefits it offers to various antibody discovery platforms using five different antigens.
Journal ArticleDOI
Study on Critical Parameters of Nitrogen Injection during In Situ Modification in Oil Shale
TL;DR: In this paper , the critical nitrogen injection rate under various working conditions, such as different well types, different wellhead steam parameters, and insulation pipe parameters, was not fully considered and studied.