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Xiaogang Zhong
Researcher at Georgetown University
Publications - 23
Citations - 1317
Xiaogang Zhong is an academic researcher from Georgetown University. The author has contributed to research in topics: Cancer & Transcriptome. The author has an hindex of 10, co-authored 23 publications receiving 1133 citations. Previous affiliations of Xiaogang Zhong include Georgetown University Medical Center & University of Washington.
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Journal ArticleDOI
Plasma phospholipids identify antecedent memory impairment in older adults
Mark Mapstone,Amrita K. Cheema,Massimo S. Fiandaca,Xiaogang Zhong,Timothy R. Mhyre,Linda MacArthur,William J. Hall,Susan G. Fisher,Derick R. Peterson,James M Haley,Michael Nazar,Steven A. Rich,Dan J Berlau,Carrie B. Peltz,Ming Tan,Claudia H. Kawas,Howard J. Federoff +16 more
TL;DR: This work discovered and validated a set of ten lipids from peripheral blood that predicted phenoconversion to either amnestic mild cognitive impairment or Alzheimer's disease within a 2–3 year timeframe with over 90% accuracy and may be sensitive to early neurodegeneration of preclinical Alzheimer’s disease.
Journal ArticleDOI
Plasma 24-metabolite Panel Predicts Preclinical Transition to Clinical Stages of Alzheimer’s Disease
Massimo S. Fiandaca,Xiaogang Zhong,Amrita K. Cheema,Michael H. Orquiza,Swathi Chidambaram,Ming Tan,Carole Roan Gresenz,Kevin Fitzgerald,Mike A. Nalls,Andrew B. Singleton,Mark Mapstone,Howard J. Federoff +11 more
TL;DR: Through inclusion of additional significantly dysregulated analyte species, the new biomarker panel provides greater accuracy in the authors' cohort but remains limited by predictive power.
Journal ArticleDOI
Cross-study validation and combined analysis of gene expression microarray data.
TL;DR: It is illustrated that it is possible to identify a substantial biologically relevant subset of the human genome within which hybridization results are reliable and to develop simple expression measures that allow comparison across platforms, studies, laboratories and populations.
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Conditionally reprogrammed normal and primary tumor prostate epithelial cells: a novel patient-derived cell model for studies of human prostate cancer
Olga A. Timofeeva,Nancy Palechor-Ceron,Guanglei Li,Hang Yuan,Ewa Krawczyk,Xiaogang Zhong,Geng Liu,Geeta Upadhyay,Aleksandra Dakic,Songtao Yu,Shuang Fang,Sujata Choudhury,Xueping Zhang,Andrew Ju,Myeong-Seon Lee,Han C. Dan,Youngmi Ji,Yong Hou,Yun-Ling Zheng,Chris Albanese,Chris Albanese,Johng S. Rhim,Richard Schlegel,Anatoly Dritschilo,Xuefeng Liu +24 more
TL;DR: Real time RT-PCR analyses suggest that CR cells maintain high levels of proliferation and low levels of differentiation in the presence of feeder cells and ROCK inhibitor, but undergo differentiation once injected into SCID mice.
Journal ArticleDOI
Metabolomic biomarkers of pancreatic cancer: a meta-analysis study.
Khyati Y. Mehta,Hung-Jen Wu,Smrithi S. Menon,Yassi Fallah,Xiaogang Zhong,Nasser Rizk,Keith Unger,Mark Mapstone,Massimo S. Fiandaca,Howard J. Federoff,Amrita K. Cheema +10 more
TL;DR: The study underscores the need for a more robust study design for cancer biomarker studies so as to maximize the translational value and clinical implementation of metabolomic biosignatures.