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Xiaojuan Deng
Researcher at South China Agricultural University
Publications - 24
Citations - 736
Xiaojuan Deng is an academic researcher from South China Agricultural University. The author has contributed to research in topics: Bombyx mori & Gene. The author has an hindex of 13, co-authored 23 publications receiving 589 citations. Previous affiliations of Xiaojuan Deng include Sun Yat-sen University & Chinese Academy of Sciences.
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Journal ArticleDOI
Autophagy precedes apoptosis during the remodeling of silkworm larval midgut
Eleonora Franzetti,Zhijun Huang,Yan-Xia Shi,Kun Xie,Xiaojuan Deng,Jian-Ping Li,Li Qingrong,Wanying Yang,Wen-Nian Zeng,Morena Casartelli,Hui-Min Deng,Silvia Cappellozza,Annalisa Grimaldi,Qingyou Xia,Gianluca Tettamanti,Yang Cao,Qili Feng +16 more
TL;DR: It is demonstrated that larval midgut degradation is due to the concerted action of the two mechanisms, which occur at different times and have different functions, and that the process of autophagy can recycle molecules from the degenerating cells and supply nutrients to the animal during the non-feeding period.
Journal ArticleDOI
20-hydroxyecdysone upregulates Atg genes to induce autophagy in the Bombyx fat body
TL;DR: It is concluded that in addition to blocking TORC1 activity for autophagosome initiation, 20E upregulates Atg genes to induce autophagy in the Bombyx fat body.
Journal ArticleDOI
BmATG5 and BmATG6 mediate apoptosis following autophagy induced by 20-hydroxyecdysone or starvation.
Kun Xie,Ling Tian,Xinyu Guo,Kang Li,Jian-Ping Li,Xiaojuan Deng,Li Qingrong,Qingyou Xia,Yangjin Zhong,Zhijun Huang,Ji-Ping Liu,Sheng Li,Wanying Yang,Yang Cao +13 more
TL;DR: Being cleaved into BmATG5-tN and Bm ATG6-C, BmAtG5 and B mATG6 mediate apoptosis following autophagy induced by 20E or starvation in Bombyx Bm-12 cells, reflecting that autophileagy precedes apoptosis in the midgut during BombyX metamorphosis.
Journal ArticleDOI
Control of Drosophila Blood Cell Activation via Toll Signaling in the Fat Body
Martin R. Schmid,Ines Anderl,Laura Vesala,Leena-Maija Vanha-aho,Xiaojuan Deng,Mika Rämet,Dan Hultmark +6 more
TL;DR: Like in the humoral immune response, it is shown that Toll signaling in the fat body is of major importance in the Toll-dependent activation of blood cells and contributes very little to the immune response against the parasitoid wasp, Leptopilina boulardi.
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Systematic cloning and analysis of autophagy-related genes from the silkworm Bombyx mori
Xuan Zhang,Zhanying Hu,Wei-Fang Li,Li Qingrong,Xiaojuan Deng,Wanying Yang,Yang Cao,Cong-Zhao Zhou +7 more
TL;DR: Bioinformatics in combination with RT-PCR enable us to remodel a preliminary pathway of autophagy in the silkworm, suggesting that the Autophagy should play an important role in Bombyx mori silkgland.