Xiaoyan Jiang

TL;DR: The numbers and types of cells generated from chronic phase CML patients' cells transplanted into adult immunodeficient mice or fetal sheep, and from transplants of primitive murine and human hematopoietic cells transduced with a retroviral BCR‐ABL vector reinforce the importance of the autocrine IL‐3/G‐CSF mechanism in the development of CML.

TL;DR: A new scale for assessment of frailty and compare the clinical features between the new scale and the conventional Fried criteria revealed a significantly worse status in frail participants with CI than without.

TL;DR: CML should be the first human malignancy in which a complete medical cure is achieved through the eradication of cancer stem cells in more complex malignancies through combining the specific targeting of BCR-ABL and CML stem cells.

TL;DR: Elevated homocysteine is not a causal factor but a biomarker that manifests greater possibility of frailty in high risk elderly individuals for prevention.

TL;DR: This one-day symposium was held at the BC Cancer Research Centre in Vancouver, BC, bringing together experts in cell biology, protein biochemistry and medicinal chemistry across several different disease models and model organisms.