Xiaoyan Jiang

TL;DR: The D and D5 haplogroups, as well as the 5178A allele, are associated with decreased eGFR levels and an increased risk of CKD in a longevous population.

TL;DR: Peripheral blood NLR levels at the time of initial diagnosis and treatment had better diagnostic and predictive value for the progression of future thrombotic events in patients with PV than age ≥ 60 years, history of previousThrombosis, and fibrinogen.

TL;DR: The fourth Vancouver Autophagy Symposium showcased research that expands the understanding of the protein interaction networks and molecular mechanisms underlying autophagy and other cellular stress responses in the context of distinct stressors.

TL;DR: It is demonstrated that a combination ofmiR-145 and miR-708 are effective predictors of NL response in treatment-naïve patients whereas miCFC output in these panels enhanced predictive performance, and this novel predictive model may be developed into a prognostic tool for use in the clinic.

TL;DR: The CML clone in chronic phase patients contains a similar hierarchy of short and longterm repopulating cells as is found in normal adult bone marrow, and that the CML repopulated cells have, in addition to their ability to sustain the clone, a greater innate resistance to the toxic effects that imatinib mesylate has in vivo on the majority population of more differentiated CML cells.