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Xiaoyan Jiang
Researcher at Tongji University
Publications - 209
Citations - 11393
Xiaoyan Jiang is an academic researcher from Tongji University. The author has contributed to research in topics: Myeloid leukemia & Stem cell. The author has an hindex of 40, co-authored 186 publications receiving 10162 citations. Previous affiliations of Xiaoyan Jiang include BC Cancer Agency & Harbin Medical University.
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Journal ArticleDOI
The Myb and Ahi-1 genes are physically very closely linked on mouse chromosome 10.
Xiaoyan Jiang,L. Villeneuve,C. Turmel,Christine A. Kozak,Paul Jolicoeur,Paul Jolicoeur,Paul Jolicoeur +6 more
TL;DR: The data have revealed that there is no clear evidence for such activation in the tumors the authors have tested, indicating that provirus insertion in the Ahi-1 region is activating a novel gene, apparently involved in tumor formation.
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Targeting AXL kinase sensitizes leukemic stem and progenitor cells to venetoclax treatment in acute myeloid leukemia
Xiaojia Niu,Katharina Rothe,Min Chen,Sarah Grasedieck,Rick Li,Sung-Eun Nam,Xiuyan Zhang,German Novakovskiy,Yehyeon Ahn,Irina A Maksakova,Shenshen Lai,Hong Zhang,Jun Yan,Hong Liu,Yun Zhao,Depei Wu,Yubin Ge,Wyeth W. Wasserman,Arefeh Rouhi,Florian Kuchenbauer,Calvin K. Yip,Zaihui Zhang,Xiaoyan Jiang +22 more
TL;DR: In this article, the authors developed a potent selective AXL inhibitor that has favorable pharmaceutical properties and efficacy against preclinical patient-derived xenotransplantation (PDX) models of AML.
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Application of engineered extracellular vesicles for targeted tumor therapy
Fusheng Zhang,Jinshuai Guo,Zhenghou Zhang,Meiqi Duan,Guang-Ting Wang,Yiping Qian,Haiying Zhao,Zhi Yang,Xiaoyan Jiang +8 more
TL;DR: In this paper , the therapeutic potential of EVs in tumors, including engineered extracellular vesicles and EVs' co-delivery systems, is evaluated, and the authors discuss the isolation technologies of EVs, as well as engineering approaches to their modification.
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Precision autophagy: Will the next wave of selective autophagy markers and specific autophagy inhibitors feed clinical pipelines?
Chandra Lebovitz,Lindsay DeVorkin,Damien Bosc,Katharina Rothe,Jagbir Singh,Marcel B. Bally,Xiaoyan Jiang,Robert N. Young,Julian J. Lum,Sharon M. Gorski +9 more
TL;DR: VAS 2014 stimulated interdisciplinary discussions focused on the development of biomarkers, drugs, and preclinical models to facilitate clinical translation of key autophagy discoveries, and revealed novel Autophagy regulators and receptors in metabolic diseases, proteinopathies, and cancer.
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Aberrantly Expressed lncRNAs in Primary Varicose Great Saphenous Veins
Xiang Li,Xiaoyan Jiang,Jin Ge,Jing Wang,Guo-Jun Chen,Liang Xu,Duanyang Xie,Tianyou Yuan,Dasheng Zhang,Hong Zhang,Yi-Han Chen +10 more
TL;DR: Aberrantly expressed lncRNAs involved in the prevalence of GSV varicosities were identified and validated and their functions were predicted and provided novel insight into the physiology of lnc RNAs and the pathogenesis of varicose veins for further investigation.