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Xudong Xu
Researcher at Peking Union Medical College
Publications - 169
Citations - 2180
Xudong Xu is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 20, co-authored 136 publications receiving 1609 citations. Previous affiliations of Xudong Xu include Chinese Ministry of Education.
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Discovery and synthesis of novel beesioside I derivatives with potent anti-HIV activity.
Haifeng Wu,Guo-Xu Ma,Qinwen Yang,Yin-Di Zhu,Li Huang,Tian Yu,Xiaoming Yang,Meng-Han Zhang,Chin Ho Chen,Susan L. Morris-Natschke,Meihua Yang,Xudong Xu,Kuo Hsiung Lee,Kuo Hsiung Lee +13 more
TL;DR: Compound 13g was the most potent compound with an EC50 value of 0.025 μM and TI value greater than 800, comparable to those of 3-O-(3',3'-dimethylsuccinyl)-betulinic acid (DSB, bevirimat). Other analogues exhibited strong to weak inhibition of HIV-1 replication in MT-4 cells.
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Structure elucidation of a new cycloartane triterpene glycoside from Souliea vaginata by NMR.
Haifeng Wu,Haifeng Wu,Yin-Di Zhu,Zhong-Hao Sun,Guo-Xu Ma,Xudong Xu,Yi-Lin Liu,Zheng-Hong Luo,Qiong-Yu Zou,Zi-Jian Zhao +9 more
TL;DR: This paper presents a meta-analyses of the chiral stationary phase of the H2O2/O2 complex, which has the potential to transform into a single substance called a “tetrahedron” which can be converted into a female sex hormone through the “love Triangle” during the courtship process.
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Supramolecular assemblies based on natural small molecules: Union would be effective
Yong Hou,Linjun Zou,Qinglong Li,Mei-Hui Chen,Haonan Ruan,Zhaocui Sun,Xudong Xu,Jun-Shan Yang,Guoxu Ma +8 more
TL;DR: In this paper , a review of the assembled mechanism of supramolecular small molecules is presented, which are mainly driven by multiple non-covalent interactions, and a new hypothesis aimed to interpret the integration effects of multi-components of traditional Chinese medicines (TCMs) inspired on the theory of suparamolecular assembly is proposed.
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Soulieoside O, a new cyclolanostane triterpenoid glycoside from Souliea vaginata.
Haifeng Wu,Peng-Fei Li,Yin-Di Zhu,Xiaopo Zhang,Guo-Xu Ma,Xudong Xu,Yi-Lin Liu,Zheng-Hong Luo,Di-Zhao Chen,Qiong-Yu Zou,Zi-Jian Zhao +10 more
TL;DR: The new compound showed moderate inhibitory activity against three human cancer cell lines with IC50 values of 9.3–22.5 μM and was isolated from the rhizomes of Souliea vaginata.
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Oleanane triterpene saponins with cardioprotective activity from Clinopodium polycephalum.
Yu-Xia Hu,Wei Zhang,Wen Zhang,Yin-Di Zhu,Guo-Xu Ma,Zhu Nailiang,Wen Sun,Ze-Xin Ma,Yu Shichun,Xudong Xu,Kai-Tuo Chen,Jun-Shan Yang +11 more
TL;DR: Two new triterpene saponins, clinopodiside VI and saikosaponin c, were isolated from the plant of Clinopodium polycephalum and showed moderate inhibition against H9c2 cell damage induced by H2O2.