Y
Yael Altuvia
Researcher at Hebrew University of Jerusalem
Publications - 28
Citations - 2918
Yael Altuvia is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: RNA & Gene. The author has an hindex of 18, co-authored 27 publications receiving 2700 citations.
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Journal ArticleDOI
Clustering and conservation patterns of human microRNAs
Yael Altuvia,Pablo Landgraf,Gila Lithwick,Naama Elefant,Sébastien Pfeffer,Alexei A. Aravin,Michael J. Brownstein,Thomas Tuschl,Hanah Margalit +8 more
TL;DR: This study raises the proportion of clustered human miRNAs that are <3000 nt apart to 42%.
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Host immune system gene targeting by a viral miRNA.
Noam Stern-Ginossar,Naama Elefant,Albert Zimmermann,Dana G. Wolf,Nivin Saleh,Moshe Biton,Elad Horwitz,Zafnat Prokocimer,Mark N. Prichard,Gabriele Hahn,Debra Goldman-Wohl,Caryn Greenfield,Simcha Yagel,Hartmut Hengel,Yael Altuvia,Hanah Margalit,Ofer Mandelboim +16 more
TL;DR: In this paper, the authors developed an algorithm for the prediction of miRNA targets and applied it to human cytomegalovirus miRNAs, resulting in the identification of the major histocompatibility complex class I-related chain B (MICB) gene as a top candidate target of hcmv-miR-UL112.
Journal ArticleDOI
Global Mapping of Small RNA-Target Interactions in Bacteria
Sahar Melamed,Asaf Peer,Raya Faigenbaum-Romm,Yair E. Gatt,Niv Reiss,Amir Bar,Yael Altuvia,Liron Argaman,Hanah Margalit +8 more
TL;DR: This work developed a broadly applicable methodology termed RIL-seq (RNA interaction by ligation and sequencing), which integrates experimental and computational tools for in vivo transcriptome-wide identification of interactions involving Hfq-associated sRNAs, and discovered an extensive network of interaction involving RNA pairs showing sequence complementarity.
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Structure-based prediction of binding peptides to MHC class I molecules: application to a broad range of MHC alleles.
TL;DR: The use of the pairwise potential table of Miyazawa and Jernigan, together with a new definition of MHC contact residues by which only residues that contribute exclusively to sequence specific binding are included, allows the development of an improved algorithm that can be applied to a wide range of M HC class I alleles.
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Ranking potential binding peptides to MHC molecules by a computational threading approach.
TL;DR: The computational procedure presented here succeeds in determining the MHC binding potential of peptides along a protein amino acid sequence, without relying on binding motifs.