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Yan-Yan Zhu
Researcher at Zhengzhou University
Publications - 1
Citations - 195
Yan-Yan Zhu is an academic researcher from Zhengzhou University. The author has contributed to research in topics: Apoptosis & Demethylase. The author has an hindex of 1, co-authored 1 publications receiving 161 citations.
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Triazole–Dithiocarbamate Based Selective Lysine Specific Demethylase 1 (LSD1) Inactivators Inhibit Gastric Cancer Cell Growth, Invasion, and Migration
Yi-Chao Zheng,Ying-Chao Duan,Jin-Lian Ma,Rui-Min Xu,Xiaolin Zi,Wen-Lei Lv,Meng-Meng Wang,Xian-Wei Ye,Shun Zhu,David L. Mobley,Yan-Yan Zhu,Jun-Wei Wang,Jinfeng Li,Zhi-Ru Wang,Wen Zhao,Hong-Min Liu +15 more
TL;DR: Five series of 1,2,3-triazole-dithiocarbamate hybrids were designed and synthesized and screened their inhibitory activity toward LSD1 and it was found that some of these compounds exhibited the most specific and robust inhibition of LSD1.