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Yan You
Researcher at Fudan University
Publications - 27
Citations - 1322
Yan You is an academic researcher from Fudan University. The author has contributed to research in topics: Subventricular zone & Ganglionic eminence. The author has an hindex of 14, co-authored 24 publications receiving 1095 citations. Previous affiliations of Yan You include Boston Children's Hospital.
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Journal ArticleDOI
Identification and characterization of neuroblasts in the subventricular zone and rostral migratory stream of the adult human brain
Congmin Wang,Fang Liu,Ying Ying Liu,Cai Hong Zhao,Yan You,Lei Wang,Jingxiao Zhang,Bin Wei,Tong Ma,Qiangqiang Zhang,Yue Zhang,Rui Chen,Hongjun Song,Zhengang Yang +13 more
TL;DR: Evidence that neuroblasts exist continuously in the anterior ventral SVZ and RMS of the adult human brain is provided and the data suggest that the SVZ maintains the ability to produce neuroblast in the adulthuman brain.
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Subcortical origins of human and monkey neocortical interneurons
Tong Ma,Congmin Wang,Lei Wang,Lei Wang,Xing Zhou,Miao Tian,Qiangqiang Zhang,Yue Zhang,Jiwen Li,Zhidong Liu,Yuqun Cai,Fang Liu,Yan You,Chao Chen,Kenneth Campbell,Hongjun Song,Lan Ma,John L.R. Rubenstein,Zhengang Yang +18 more
TL;DR: It is proposed that the majority of primate neocortical GABAergic interneurons originate from ganglionic eminences of the ventral telencephalon, and this work reveals that the mammalian neocortex shares basic rules for interneuron development, substantially reshaping the understanding of the origin and classification ofPrimate neocortex.
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Brain Injury Does Not Alter the Intrinsic Differentiation Potential of Adult Neuroblasts
TL;DR: It is shown that SVZ neuroblasts give rise almost exclusively to calretinin-expressing cells in the damaged striatum, resulting in the accumulation of these cells during long term recovery after stroke, and suggests that adult neuroblast do not alter their intrinsic differentiation potential after brain injury.
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Neonatal Hypoxic/Ischemic Brain Injury Induces Production of Calretinin-Expressing Interneurons in the Striatum
TL;DR: It is shown here that virtually all of the newly produced striatal neurons are calretinin (CR)‐immunoreactive (+), but not DARPP‐32+, calbindin‐D‐28K+, parvalbumin+, somatostatin+, or choline acetyltransferase+.
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A Subpopulation of Dorsal Lateral/Caudal Ganglionic Eminence-Derived Neocortical Interneurons Expresses the Transcription Factor Sp8
TL;DR: It is shown that the transcription factor Sp8 is expressed in one-fifth of adult cortical interneurons, which appear to be derived from both the dorsal LGE and the dorsal CGE (dLGE and dCGE, respectively), which are born at later embryonic stages and follow an outside-in layering pattern.