Q
Qiangqiang Zhang
Researcher at Fudan University
Publications - 7
Citations - 726
Qiangqiang Zhang is an academic researcher from Fudan University. The author has contributed to research in topics: Gene & Subventricular zone. The author has an hindex of 5, co-authored 5 publications receiving 656 citations.
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Journal ArticleDOI
Identification and characterization of neuroblasts in the subventricular zone and rostral migratory stream of the adult human brain
Congmin Wang,Fang Liu,Ying Ying Liu,Cai Hong Zhao,Yan You,Lei Wang,Jingxiao Zhang,Bin Wei,Tong Ma,Qiangqiang Zhang,Yue Zhang,Rui Chen,Hongjun Song,Zhengang Yang +13 more
TL;DR: Evidence that neuroblasts exist continuously in the anterior ventral SVZ and RMS of the adult human brain is provided and the data suggest that the SVZ maintains the ability to produce neuroblast in the adulthuman brain.
Journal ArticleDOI
Subcortical origins of human and monkey neocortical interneurons
Tong Ma,Congmin Wang,Lei Wang,Lei Wang,Xing Zhou,Miao Tian,Qiangqiang Zhang,Yue Zhang,Jiwen Li,Zhidong Liu,Yuqun Cai,Fang Liu,Yan You,Chao Chen,Kenneth Campbell,Hongjun Song,Lan Ma,John L.R. Rubenstein,Zhengang Yang +18 more
TL;DR: It is proposed that the majority of primate neocortical GABAergic interneurons originate from ganglionic eminences of the ventral telencephalon, and this work reveals that the mammalian neocortex shares basic rules for interneuron development, substantially reshaping the understanding of the origin and classification ofPrimate neocortex.
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A Subpopulation of Dorsal Lateral/Caudal Ganglionic Eminence-Derived Neocortical Interneurons Expresses the Transcription Factor Sp8
TL;DR: It is shown that the transcription factor Sp8 is expressed in one-fifth of adult cortical interneurons, which appear to be derived from both the dorsal LGE and the dorsal CGE (dLGE and dCGE, respectively), which are born at later embryonic stages and follow an outside-in layering pattern.
Journal ArticleDOI
Nuclear receptor COUP‐TFII‐expressing neocortical interneurons are derived from the medial and lateral/caudal ganglionic eminence and define specific subsets of mature interneurons
Yuqun Cai,Qiangqiang Zhang,Congmin Wang,Yue Zhang,Tong Ma,Xing Zhou,Miao Tian,John L.R. Rubenstein,Zhengang Yang +8 more
TL;DR: It is demonstrated that the POA and ventral MGE do not give rise to COUP‐TFII+ neocortical interneurons, suggesting that the dMGE is the source of COUP'SOM+/somatostatin+/SOM+, which are mainly located in layer V of the adult neocortex.
Journal ArticleDOI
The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons
Qiangqiang Zhang,Yue Zhang,Chunyang Wang,Zhejun Xu,Qifei Liang,Lei An,Jiwen Li,Zhidong Liu,Yan You,Miao He,Ying Mao,Bin Chen,Zhi-Qi Xiong,John L.R. Rubenstein,Zhengang Yang +14 more
TL;DR: RNA-seq and in situ hybridization reveal that Sp9 promotes expression of Adora2a, P2ry1, Gpr6, and Grik3 in the LGE and striatum, and is crucial for the generation, differentiation, and survival of striatopallidal MSNs.