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Yang Do Choi
Researcher at Northwestern University
Publications - 10
Citations - 1438
Yang Do Choi is an academic researcher from Northwestern University. The author has contributed to research in topics: Ribonucleoprotein & RNA. The author has an hindex of 8, co-authored 10 publications receiving 1409 citations.
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Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins.
TL;DR: The detailed analysis of the protein composition of immunopurified hnRNP particles from human HeLa cells is reported here on, suggesting that most, if not all, of these proteins are single-stranded nucleic acid-binding proteins.
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Heterogeneous nuclear ribonucleoproteins: role in RNA splicing.
TL;DR: An essential role for proteins of the hnRNP complex in the splicing of mRNA precursors is indicated, and a 60S splicing complex does not form in a C protein-depleted nuclear extract.
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Physical change in cytoplasmic messenger ribonucleoproteins in cells treated with inhibitors of mRNA transcription.
TL;DR: It is demonstrated that commonly used inhibitors of transcription affect the physical state of messenger ribonucleoproteins in vivo.
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Characterization of heterogeneous nuclear RNA-protein complexes in vivo with monoclonal antibodies.
TL;DR: The monoclonal antibodies recognized similar proteins in human and monkey cells but not in several other vertebrates, and it was demonstrated that these proteins are segregated to the nucleus, where they are part of a fine particulate nonnucleolar structure.
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Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex (hnRNP): a unique supramolecular assembly.
Yang Do Choi,Gideon Dreyfuss +1 more
TL;DR: Nuclease digestions indicate that RNA plays a role in maintaining the integrity of the structure and that intact RNA of approximately equal to 125 nucleotides is sufficient to hold the complex of proteins together.