Y
Yang She
Researcher at Chinese Academy of Sciences
Publications - 7
Citations - 1766
Yang She is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Chemistry & Nitrogen. The author has an hindex of 3, co-authored 4 publications receiving 1011 citations.
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Journal ArticleDOI
Pore-forming activity and structural autoinhibition of the gasdermin family
Jingjin Ding,Kun Wang,Wang Liu,Yang She,Qi Sun,Jianjin Shi,Hanzi Sun,Da-Cheng Wang,Da-Cheng Wang,Feng Shao +9 more
TL;DR: It is demonstrated that the liposome-leakage and pore-forming activities of the gasdermin-N domain are required for pyroptosis and provide insights into the roles of theGasdermin family in necrosis, immunity and diseases.
Journal ArticleDOI
Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose
Ping Zhou,Yang She,Na Dong,Peng Li,Huabin He,Alessio Borio,Qingcui Wu,Shan Lu,Xiaojun Ding,Yong Cao,Yue Xu,Wenqing Gao,Meng-Qiu Dong,Jingjin Ding,Da-Cheng Wang,Alla Zamyatina,Feng Shao,Feng Shao +17 more
TL;DR: This work combined a transposon screen in Yersinia pseudotuberculosis with biochemical analyses and identified ADP-β-d-manno-heptose (ADP-Hep), which mediates type III secretion system-dependent NF-κB activation and cytokine expression.
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Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers
Alexander X. Jones,Yong Cao,Yuliang Tang,Jian-Hua Wang,Yue-He Ding,Hui Tan,Zhen-Lin Chen,Run-Qian Fang,Yin Jili,Rongchang Chen,Xing Zhu,Yang She,Niu Huang,Feng Shao,Keqiong Ye,Rui-Xiang Sun,Si-Min He,Xiaoguang Lei,Meng-Qiu Dong +18 more
TL;DR: Arg-Arg and Lys-Arg cross-linkers are developed, which provide structural information elusive to the widely used Lys-Lys cross-links, which can provide insights into protein structures and interactions.
Journal ArticleDOI
Structural mechanisms for regulation of GSDMB pore-forming activity
Xiu-Li Zhong,Huiyan Zeng,Zhiwei Zhou,Ya Su,Hang Cheng,Yan-Jie Hou,Yang She,Na Feng,Feng Shao,Jingjin Ding +9 more