Li Yang

TL;DR: It is found that immunotherapy with qVEGFR was effective at protective and therapeutic antitumor immunity in several solid and hematopoietic tumor models in mice, and may provide a vaccine strategy for cancer therapy through the induction of autoimmunity against the growth factor receptor associated with angiogenesis in a cross-reaction with single xenogeneic homologous protein.

TL;DR: Treatment of tumor-bearing mice with a truncated human basic fibroblast growth factor peptide and a FGFR-mediated drug delivery system may provide a new treatment strategy for tumors which overexpress FGFRs are suggested.

TL;DR: It is shown here that vaccination with Xenopus FGFR-1 (pxFR1) is effective at antitumor immunity in three murine models, and may provide a new vaccine strategy for cancer therapy through the induction of autoimmunity against FG FR-1 associated with angiogenesis in a cross-reaction.

TL;DR: Findings may provide a new vaccine strategy for the treatment of EGFr-positive tumors through the induction of the autoimmune response against EGFr in a cross-reaction between the xenogeneic homologous and self EGFr.

TL;DR: In this paper, the synergistic effects of basic fibroblast growth factor (FGF-2) and platelet-derived growth factor BB (PDGF-BB) proteins together establish functional and stable vascular networks on mouse corneal and also in animal model of hindlimb ischemia.